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Bladder Cancer clinical trials in New York City, NY

35 studies for Bladder Cancer are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06770582

Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

RecruitingPhase 3
  • Veterans Affairs New York Harbor Healthcare System-Manhattan Campus, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07000084

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute), New York
  • NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute), New York
  • Icahn School of Medicine at Mount Sinai, New York
  • and 2 more
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center ( Site 5031), New York
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07232602

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Memorial Sloan Kettering Hospital, New York
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

RecruitingPhase 2
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 0111), New York
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06833073

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

RecruitingPhase 2
  • NYP/Weill Cornell Medical Center, New York
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07061964

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
  • NYP/Weill Cornell Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

RecruitingPhase 1/2
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07421700

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

RecruitingPhase 1
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street)., New York
  • Memorial Sloan Kettering Cancer Center 53rd street, New York
  • Icahn School of Medicine at Mount Sinai, New York
  • and 3 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07206225

A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)

RecruitingPhase 3
  • Memorial Sloan Kettering Cancer Center ( Site 0832), New York
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07419295

A Study of Surgical Techniques During Cystectomy

RecruitingPhase 3
  • Memorial Sloan Kettering Cancer Center (All Protocol Activites), New York
Ages 21 and older · All sexes · Updated Sep 22, 2026 · NCT06703476

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

RecruitingPhase 3
  • Columbia University Irving Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
  • Weill Cornell Medical College, New York
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

RecruitingPhase 1
  • Icahn School of Medicine at Mount Sinai, New York
  • Columbia University Irving Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07217171

First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06644755

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

RecruitingPhase 2
  • Integrated Medical Professionals, PLLC (Solaris), New York
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06567743

A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue

Recruiting
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05837767

Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

RecruitingPhase 2
  • Laura & Isaac Perlmutter Cancer Center - NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT05951179

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

RecruitingPhase 1
  • New York University (NYU), New York
  • Weill Cornell Medicine, New York
  • Icahn School of Medicine at Mount Sinai, New York
  • and 2 more
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05614739

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

RecruitingPhase 3
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07097142

A Study of a Side Effects and Resource Navigation Program for People With Cancer

Recruiting
  • City College of New York (Data Collection AND Specimen Analysis), New York
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07646847

Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy

RecruitingPhase 2/3
  • Icahn School of Medicine at Mount Sinai, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT07106762

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • Columbia University Irving Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street)., New York
  • Icahn School of Medicine at Mount Sinai, New York
  • Evelyn H. Lauder Breast and Imaging Centre (BAIC), New York
  • and 2 more
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT04879329

An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC

RecruitingPhase 3
  • Research Site, New York
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07720284

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • North Shore Hematology Oncology Associates P.C. DBA New York Cancer and Blood Specialists, New York
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

Recruiting
  • Integrated Medical Professionals, New York
Ages 18 to 88 · All sexes · Updated Jul 2, 2026 · NCT06394869

A Study of 68Gallium PSMA-PET/CT Scans in People With Bladder Cancer or Skin Cancer

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT05562791

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

Blue Light Cystoscopy With Cysview® Registry

RecruitingObservational study
  • NYU Langone's Perlmutter Cancer Center, New York
Ages 18 and older · All sexes · Updated Dec 18, 2025 · NCT02660645

Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion

Recruiting
  • Mount Sinai Hospital, New York
Ages 18 and older · All sexes · Updated Dec 15, 2025 · NCT06689176

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, New York
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Gemcitabine/Cisplatin Plus Cemiplimab With or Without Fianlimab in Localized Muscle-invasive Bladder Cancer (NeoSTOP-IT)

RecruitingPhase 2
  • Columbia University Irving Medical Center/ New York Presbyterian Hospital, New York
Ages 18 and older · All sexes · Updated Sep 2, 2025 · NCT06571708

About Bladder Cancer

Bladder cancer symptoms range from lower back pain to blood in your urine. Read about important risk factors and find a list of treatments available

More about Bladder Cancer on MedlinePlus

Bladder Cancer trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.