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Liver Cancer clinical trials in Cleveland, OH

11 studies for Liver Cancer are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

National Liver Cancer Screening Trial

RecruitingPhase 4
  • The Cleveland Clinic, Cleveland
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06084234

A Study Evaluating a New Radiation Treatment Workflow (NGDS)

Recruiting
  • University Hospital Cleveland Medical Center, Cleveland
Ages 21 and older · All sexes · Updated Sep 17, 2026 · NCT07824583

EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.

Recruiting
  • University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06263088

Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis

Recruiting
  • Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07044362

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

RecruitingObservational study
  • Cleveland Clinic Foundation, Cleveland
Ages 22 and older · All sexes · Updated Sep 11, 2026 · NCT06486454

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

RecruitingPhase 1
  • Clinical Trial Site, Cleveland
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06600321

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

Recruiting
  • Louis Stokes VA Medical Center, Cleveland, OH, Cleveland
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572

68Ga-PSMA-11 PET-directed Radioligand Therapy in Metastatic Hepatocellular Carcinoma (HCC)

RecruitingPhase 2
  • Case Comprehensive Cancer Center, University Hospitals Cleveland Medical Center, Seidman Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT06852820

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Mayfield Heights · 12 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Liver Cancer

The most common form of liver cancer in adults is hepatocellular carcinoma. Learn about diagnosis, treatment and taking part in research studies.

More about Liver Cancer on MedlinePlus

Liver Cancer trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.