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Kidney Cancer (Renal Cell Carcinoma) clinical trials in Chicago, IL

8 studies for Kidney Cancer (Renal Cell Carcinoma) are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mount Sinai Hospital Medical Center, Chicago
  • John H Stroger Jr Hospital of Cook County, Chicago
  • University of Illinois, Chicago
  • and 1 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #26, Chicago
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Rush MD Anderson Cancer Center, Chicago
  • University of Chicago Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

RecruitingPhase 2
  • Northwestern University, Chicago
  • University of Chicago Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05327686

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

RecruitingPhase 3
  • Northwestern University, Chicago
  • Rush MD Anderson Cancer Center, Chicago
  • University of Illinois, Chicago
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06661720

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Xencor Investigative Site, Chicago
  • Xencor Investigative Site, Chicago
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

RecruitingPhase 3
  • Northwestern University, Chicago
  • Rush University Medical Center, Chicago
  • University of Illinois, Chicago
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT04510597

Kidney Cancer (Renal Cell Carcinoma) trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.