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Kidney Cancer (Renal Cell Carcinoma) clinical trials in Cleveland, OH

14 studies for Kidney Cancer (Renal Cell Carcinoma) are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors

RecruitingPhase 1
  • Research Site, Cleveland
  • Research Site, Cleveland
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT05536141

Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • NEO-811 Cleveland Site, Cleveland
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07300241

A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

RecruitingPhase 1
  • University Hospitals Cleveland Medical Center, Cleveland
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06234605

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #10, Cleveland
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

RecruitingPhase 2
  • Case Western Reserve University, Cleveland
  • UHHS-Chagrin Highlands Medical Center, Beachwood · 10 mi away
  • UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor · 22 mi away
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05327686

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

RecruitingPhase 3
  • Case Western Reserve University, Cleveland
  • UHHS-Chagrin Highlands Medical Center, Beachwood · 10 mi away
  • UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor · 22 mi away
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06661720

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

RecruitingPhase 2
  • University Hospitals Seidman Cancer Center, Cleveland
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05361720

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

RecruitingPhase 1
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06966024

A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

RecruitingPhase 1
  • Case Comprehensive Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Sep 23, 2025 · NCT06805825

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

RecruitingPhase 3
  • Case Western Reserve University, Cleveland
  • UHHS-Chagrin Highlands Medical Center, Beachwood · 10 mi away
  • UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor · 22 mi away
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT04510597

Kidney Cancer (Renal Cell Carcinoma) trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.