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Liver Cancer (Hepatocellular Carcinoma) clinical trials in Philadelphia, PA

16 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #98, Philadelphia
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

National Liver Cancer Screening Trial

RecruitingPhase 4
  • University of Pennsylvania, Philadelphia
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06084234

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

RecruitingPhase 3
  • Research Site, Philadelphia
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06921785

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Children's Hospital of Philadelphia, Philadelphia
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of Pennsylvania, Perelman School of Medicine, Philadelphia
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

RecruitingPhase 3
  • Christiana Care Health System-Concord Health Center, Chadds Ford · 23 mi away
  • Christiana Care Health System-Wilmington Hospital, Wilmington · 25 mi away
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07166406

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • Thomas Jefferson University, Philadelphia
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

Recruiting
  • Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572

Y-90 Treatment Response Using Transarterial Radioembolization

RecruitingPhase 2
  • Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, Philadelphia
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT07145801

Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer

RecruitingPhase 1/2
  • University of Pennsylvania, Philadelphia
Ages 20 to 99 · All sexes · Updated Apr 20, 2026 · NCT02174549

Targeting Ischemia-Induced Autophagy Dependence in Hepatocellular Carcinoma

RecruitingPhase 1/2
  • Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT05842174

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

RecruitingPhase 2
  • University of Pennsylvania, Abramson Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Apr 2, 2026 · NCT05733598

SBRT With Atezo/Bev for HCC

RecruitingPhase 1
  • Abramson Cancer Center of the University of Pennsylvania, Philadelphia
Ages 18 to 99 · All sexes · Updated Feb 20, 2026 · NCT05488522

Development of 3D Multi-Parametric Ultrasound (MPUS) as a Decision Support Tool for Patients

RecruitingObservational study
  • Thomas Jefferson Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Jan 26, 2026 · NCT05705219

Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

RecruitingPhase 4
  • Albert Einstein Healthcare Network, Philadelphia
Ages 18 to 64 · All sexes · Updated Jan 22, 2026 · NCT04373564

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Philadelphia
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Liver Cancer (Hepatocellular Carcinoma) trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.