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Esophageal Adenocarcinoma clinical trials in Chicago, IL

8 studies for Esophageal Adenocarcinoma are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

RecruitingPhase 2/3
  • Northwestern University, Chicago
  • University of Illinois, Chicago
  • Swedish Covenant Hospital, Chicago
  • and 1 more
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06203600

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

RecruitingPhase 3
  • Mount Sinai Hospital Medical Center, Chicago
  • John H Stroger Jr Hospital of Cook County, Chicago
  • University of Illinois, Chicago
  • and 2 more
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05677490

Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

RecruitingPhase 2/3
  • Illinois Cancer Specialists, Chicago
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07392892

Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

Recruiting
  • Northwestern Memorial Hospital, Chicago
Ages 18 to 89 · All sexes · Updated Sep 11, 2026 · NCT05753748

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • UChicago Medicine - River East, Chicago
  • The University Of Chicago, Chicago
  • University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance

Recruiting
  • Northwestern University, Chicago
Ages 18 to 89 · All sexes · Updated Jul 1, 2026 · NCT05530343

Esophageal Adenocarcinoma trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.