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Head and Neck Squamous Cell Carcinoma clinical trials in Lexington, KY

9 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Lexington (within about 30 miles). Open a study to see who can join and how to contact the study team.

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

RecruitingPhase 2/3
  • University of Kentucky, Markey Cancer Center (Site # 109), Lexington
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

RecruitingPhase 3
  • University of Kentucky Medical Center, Lexington
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07276399

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

RecruitingPhase 3
  • University of Kentucky Markey Cancer Center, Lexington
Ages 60 and older · All sexes · Updated Sep 25, 2026 · NCT04892173

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

RecruitingPhase 2
  • CommonSpirit Saint Joseph Hospital - Lexington, Lexington
  • Saint Joseph Radiation Oncology Resource Center, Lexington
  • CommonSpirit Saint Joseph Medical Center - East Lexington, Lexington
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

RecruitingPhase 2/3
  • University of Kentucky/Markey Cancer Center, Lexington
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT04333537

Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin

RecruitingPhase 3
  • University of Kentucky/Markey Cancer Center, Lexington
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07441681

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

RecruitingPhase 3
  • GSK Investigational Site, Lexington
Ages 18 and older · All sexes · Updated May 26, 2026 · NCT06256588

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • University of Kentucky Markey Cancer Center, Lexington
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Lexington

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.