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Myelofibrosis clinical trials in Boston, MA

12 studies for Myelofibrosis are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04176198

A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

RecruitingPhase 3
  • Tufts Medical Center, Boston
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07623161

A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06343805

A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis

RecruitingPhase 1/2
  • Massachusetts General Hospital (Data Collection Only), Boston
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT06773195

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 75 · All sexes · Updated Jul 28, 2026 · NCT07020533

Study of INCA036978 in Participants With Myeloproliferative Neoplasms

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07441694

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

RecruitingPhase 1
  • Dana Farber Cancer Institute, Boston
Ages 13 and older · All sexes · Updated May 5, 2026 · NCT04771572

A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms

RecruitingPhase 1
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT06034002

Momelotinib During and After HCT in Myelofibrosis

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07104799

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

RecruitingPhase 2Healthy volunteers welcome
  • DFCI/BWH Brigham and Women's Hospital, Boston
Ages 18 to 75 · All sexes · Updated Mar 10, 2026 · NCT06059391

Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

RecruitingPhase 3
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 25, 2025 · NCT06479135

Myelofibrosis trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.