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Pancreatic Cancer clinical trials in Columbus, OH

18 studies for Pancreatic Cancer are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

RecruitingPhase 1
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05372614

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

RecruitingPhase 3
  • Investigative Site US033, Columbus
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07522073

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

RecruitingPhase 3
  • Facilities Design and Construction - Energy Advancement and Innovation Center, Columbus
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07409272

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

RecruitingObservational study
  • Nationwide Children's Hospital, Columbus
Up to age 17 · All sexes · Updated Sep 11, 2026 · NCT06651580

Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

RecruitingObservational study
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 50 to 75 · All sexes · Updated Sep 4, 2026 · NCT04239573

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1
  • The Ohio State University (OSU) Wexner Medical Center, Columbus
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

RecruitingPhase 3
  • Ohio State University Comprehensive Cancer Center, Columbus
  • Dublin Methodist Hospital, Dublin · 11 mi away
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06958328

Pancreatic Cancer Early Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • The Ohio State University, Columbus
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

Ultra-High Resolution Optical Coherence Tomography in Detecting Micrometer Sized Early Stage Pancreatic Cancer in Participants With Pancreatic Cancer

Recruiting
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03711890

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • The Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

RecruitingPhase 1
  • Ohio State University-James Cancer Hospital and Solove Research Institute, Columbus
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT04890613

Evaluation of Endoscopic Ultrasound-Guided Radiofrequency Ablation for the Management of Pancreatic Tumors, ERASE Study

Recruiting
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Mar 23, 2026 · NCT05961982

Disposable Perfusion Phantom for Accurate DCE (Dynamic Contrast Enhanced)-MRI Measurement of Pancreatic Cancer Therapy Response

Recruiting
  • The Ohio State University, Columbus
Ages 19 and older · All sexes · Updated Feb 27, 2026 · NCT04588025

A Brief Psychological Intervention to Improve Emotional Well-Being During Neoadjuvant Therapy for Pancreatic Cancer

Recruiting
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Feb 19, 2026 · NCT07124611

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

RecruitingPhase 2
  • Ohio State University Comprehensive Cancer Center, Columbus
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT06906562

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Columbus
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Confocal Laser Endomicroscopy as an Imaging Biomarker for the Diagnosis of Pancreatic Cystic Lesions

RecruitingObservational study
  • The Ohio State University Wexner Medical Center, Columbus
Ages 18 and older · All sexes · Updated Aug 22, 2025 · NCT03492151

About Pancreatic Cancer

The pancreas is a gland behind your stomach that produces insulin. Pancreatic cancer is hard to catch early. Find out about risk factors and symptoms.

More about Pancreatic Cancer on MedlinePlus

Pancreatic Cancer trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.