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Breast Cancer clinical trials in Columbus, OH
39 studies for Breast Cancer are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.
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Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
RecruitingPhase 3
- The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solovev Research Institute (OSUCCC - , Columbus
A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With Early-stage and Advanced HR+ Breast Cancer
RecruitingPhase 1
- The Mark H. Zangmeister Center-Mid Ohio Oncology/Hematology, Inc., Columbus
Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)
RecruitingPhase 4
- Ohio State University Comprehensive Cancer Center, Columbus
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
RecruitingPhase 1/2
- The Ohio State University Comprehensive Cancer Center, Columbus
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
RecruitingPhase 3
- The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer -T, Columbus
E-Mindfulness Approaches for Living After Breast Cancer
RecruitingPhase 3
- Ohio State University Comprehensive Cancer Center, Columbus
- Mount Carmel East Hospital, Columbus
- Mount Carmel Grove City Hospital, Grove City · 7 mi away
- and 2 more
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
RecruitingObservational studyHealthy volunteers welcome
- Ohio State University Comprehensive Cancer Center, Columbus
- Mount Carmel East Hospital, Columbus
- The Mark H Zangmeister Center, Columbus
- and 8 more
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
RecruitingPhase 1/2
- Ohio State University Comprehensive Cancer Center (OSUCCC)- The James Cancer Hospital and Solove Research Institute, Columbus
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
RecruitingObservational study
- Memorial Hospital, Marysville · 27 mi away
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
RecruitingPhase 1
- The Ohio State University (OSU) Wexner Medical Center, Columbus
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
RecruitingPhase 3
- Ohio State University Comprehensive Cancer Center, Columbus
- Columbus Oncology and Hematology Associates Inc, Columbus
- Riverside Methodist Hospital, Columbus
- and 8 more
Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease
RecruitingPhase 2
- Ohio State University, Stefanie Spielman Comprehensive Breast Center, Columbus
BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors
RecruitingPhase 1
- James Cancer Hospital and Solove Research Institute, Columbus
DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY
RecruitingPhase 2
- The Ohio State University, Columbus
Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)
RecruitingPhase 3
- Stefanie Spielman Comprehensive Breast Center at Olentangy River Road, Columbus
Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors
RecruitingPhase 1
- The Ohio State University, Columbus
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
RecruitingPhase 2
- The Ohio State University, Stefanie Spielman Comprehensive Breast Center, Columbus
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
RecruitingPhase 3
- Clinical Trial Site, Columbus
- Clinical Trial Site, Columbus
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
RecruitingPhase 1/2
- Local Institution - 0102, Columbus
ATEMPT 2.0: Adjuvant T-DM1 vs TH
RecruitingPhase 2
- Stefanie Spielman Comprehensive Breast Center, Columbus
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
RecruitingPhase 3
- Ohio State University Comprehensive Cancer Center, Columbus
Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
RecruitingPhase 2Healthy volunteers welcome
- Ohio State University Comprehensive Cancer Center, Columbus
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
RecruitingPhase 2
- The Ohio State University Comprehensive Cancer Center (OSUCCC) - The James Cancer Hospital and Solove Research Institute, Columbus
Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer
RecruitingPhase 2
- Ohio State University Comprehensive Cancer Center, Columbus
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
RecruitingPhase 1/2
- Stefanie Spielman Comprehensive Breast Center, Columbus
Impact of Dietary Inflammatory Potential on Breast Cancer Risk
RecruitingObservational study
- Ohio State University Comprehensive Cancer Center, Columbus
Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation
RecruitingPhase 1
- Ohio State University-James Cancer Hospital and Solove Research Institute, Columbus
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
RecruitingPhase 2
- The Ohio State University, Stefanie Spielman Comprehensive Breast Center, Columbus
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
RecruitingPhase 2
- Ohio State University Medical Center, Columbus
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
RecruitingPhase 3
- Ohio State University Comprehensive Cancer Center, Columbus
- Mount Carmel East Hospital, Columbus
- Riverside Methodist Hospital, Columbus
- and 8 more
Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
RecruitingObservational study
- Ohio State University Comprehensive Cancer Center, Columbus
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
RecruitingPhase 1/2
- Stefanie Spielman Comprehensive Breast Center, Columbus
Living Well With Advanced Breast Cancer
RecruitingObservational studyHealthy volunteers welcome
- Ohio State University Comprehensive Cancer Center, Columbus
Feasibility Study of CBCT for IGRT in Cancer Patients
Recruiting
- James Outpatient Center, Columbus
- Ohio State University, Brain and Spine Hospital, Columbus
- The Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus
- and 1 more
The Sleep After Breast Cancer (ABC) Study - Examining Sleep Changes and Biomarkers Among Breast Cancer Patients
RecruitingObservational study
- Ohio State University Comprehensive Cancer Center, Columbus
The Ohio State University (OSU) SCREEN Community Program
RecruitingHealthy volunteers welcome
- Ohio State University Comprehensive Cancer Center, Columbus
A Study of MT-4561 in Patients With Various Advanced Solid Tumors
RecruitingPhase 1/2
- The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center, Columbus
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, Columbus
Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer
Recruiting
- Ohio State University Comprehensive Cancer Center, Columbus
About Breast Cancer
Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. Learn about the types, diagnosis, and treatments.
More about Breast Cancer on MedlinePlus
Breast Cancer trials in other cities
- New York City, NY144 studies
- Houston, TX126 studies
- Boston, MA110 studies
- Nashville, TN78 studies
- Los Angeles, CA73 studies
- Edison, NJ70 studies
- Queens, NY67 studies
- Durham, NC63 studies
- St. Louis, MO63 studies
- Chicago, IL59 studies
- Dallas, TX54 studies
- Philadelphia, PA51 studies
Other studies in Columbus
- Non-Small Cell Lung Cancer57 studies
- Cancer (all types)40 studies
- Ovarian Cancer39 studies
- Lung Cancer36 studies
- Acute Myeloid Leukemia34 studies
- Chronic Lymphocytic Leukemia29 studies
- Metastatic Cancer25 studies
- Multiple Myeloma25 studies
- Prostate Cancer25 studies
- Endometrial Cancer24 studies
- Colorectal Cancer24 studies
- Melanoma21 studies
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.