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Colorectal Cancer clinical trials in Columbus, OH
24 studies for Colorectal Cancer are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.
A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors
RecruitingPhase 1
- ALX Center 10, Columbus
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
RecruitingObservational study
- The Ohio State University Comprehensive Cancer Center, Columbus
Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
RecruitingPhase 3
- Ohio State University Comprehensive Cancer Center, Columbus
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
RecruitingPhase 2/3
- The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center, Columbus
Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer
RecruitingPhase 1
- Ohio State University Comprehensive Cancer Center, Columbus
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
RecruitingPhase 2
- Research Site, Columbus
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
RecruitingPhase 3
- Ohio State University-Arthur G James Comprehensive Cancer Center, Columbus
- Ohio Health, Columbus
- Zangmeister Center, Columbus
Testing for Safety and Colorectal Cancer Preventive Effects of ONC201
RecruitingPhase 1
- Ohio State University Comprehensive Cancer Center, Columbus
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
RecruitingPhase 1
- The Ohio State University (OSU) Wexner Medical Center, Columbus
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial
RecruitingPhase 2
- Ohio State University Comprehensive Cancer Center, Columbus
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
RecruitingObservational studyHealthy volunteers welcome
- Ohio State University Comprehensive Cancer Center, Columbus
- Mount Carmel East Hospital, Columbus
- The Mark H Zangmeister Center, Columbus
- and 8 more
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
RecruitingPhase 1/2
- The Ohio State University Comprehensive Cancer Center, Columbus
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
RecruitingPhase 1/2
- Ohio State University, Columbus
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
RecruitingPhase 2
- The Ohio State University Comprehensive Cancer Center, Columbus
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
RecruitingPhase 4
- Zangmeister Cancer Center, Columbus
Lead-212 PSV359 Therapy for Patients With Solid Tumors
RecruitingPhase 1/2
- Ohio State University, Columbus
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
RecruitingPhase 1/2
- The Ohio State University Comprehensive Cancer Center, Columbus
KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
RecruitingPhase 1
- Ohio State University, Columbus
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
RecruitingPhase 1/2
- Stefanie Spielman Comprehensive Breast Center, Columbus
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
RecruitingObservational study
- Memorial Hospital, Marysville · 27 mi away
Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
RecruitingObservational study
- The Mark H Zangmeister Center, Columbus
The Ohio State University (OSU) SCREEN Community Program
RecruitingHealthy volunteers welcome
- Ohio State University Comprehensive Cancer Center, Columbus
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
RecruitingPhase 1/2
- The Ohio State University, Columbus
Tempus CRC Surveillance Study: A ctDNA Biomarker Profiling Study of Patients With CRC Using NGS Assays
RecruitingObservational study
- Ohio State University, Columbus
- OhioHealth Research Institute, Columbus
About Colorectal Cancer
Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.
More about Colorectal Cancer on MedlinePlus
Colorectal Cancer trials in other cities
- Houston, TX103 studies
- New York City, NY77 studies
- Nashville, TN68 studies
- Boston, MA63 studies
- Los Angeles, CA59 studies
- Arlington, VA52 studies
- St. Louis, MO49 studies
- San Antonio, TX46 studies
- Philadelphia, PA44 studies
- Grand Rapids, MI40 studies
- Baldwin Park, CA38 studies
- Seattle, WA34 studies
Other studies in Columbus
- Non-Small Cell Lung Cancer55 studies
- Cancer (all types)39 studies
- Breast Cancer39 studies
- Ovarian Cancer39 studies
- Lung Cancer36 studies
- Acute Myeloid Leukemia34 studies
- Chronic Lymphocytic Leukemia29 studies
- Metastatic Cancer27 studies
- Endometrial Cancer26 studies
- Multiple Myeloma24 studies
- Prostate Cancer24 studies
- Melanoma21 studies
From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.