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Post-Traumatic Stress Disorder clinical trials in Chicago, IL

10 studies for Post-Traumatic Stress Disorder are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)

RecruitingPhase 3
  • Uptown Research Institute, Chicago
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07456696

Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress

Recruiting
  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Ages 8 to 18 · All sexes · Updated Sep 15, 2026 · NCT07483333

Massed Prolonged Exposure for PTSD in Substance Use Treatment

Recruiting
  • Hines VA Healthcare System, Chicago
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06296186

Evaluating The Efficacy Of Combined Cognitive Processing Therapy and Stellate Ganglion Blocks for PTSD

RecruitingEarly phase 1
  • Rush University Medical Center, Chicago
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06570213

Neuromodulation and Neurorehabilitation for mTBI

Recruiting
  • Northwestern University, Chicago
Ages 18 to 80 · All sexes · Updated May 8, 2026 · NCT03819608

Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD

RecruitingPhase 2
  • Anesthesiology Pain Medicine Center, Chicago
Ages 18 and older · All sexes · Updated May 1, 2026 · NCT06608277

Nurse-Led PTSD Treatment in Primary Care

Recruiting
  • Rush University Medical Center, Chicago
Ages 18 and older · All sexes · Updated Apr 29, 2026 · NCT07430657

Patient Outcome Reporting for Timely Assessments of Life With Post-Traumatic Stress Disorder

RecruitingHealthy volunteers welcome
  • CFHC South Chicago, Chicago
  • CFHC Chicago Lawn, Chicago
Ages 18 and older · All sexes · Updated Nov 10, 2025 · NCT06479447

Preventing the Development of Chronic Pain: Treating PTSD at Acute Pain Onset

Recruiting
  • Rush University Medical Center, Chicago
Ages 18 to 70 · All sexes · Updated Oct 20, 2025 · NCT05700279

Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families

Recruiting
  • University of Illinios Chicago, Chicago
Ages 12 to 55 · All sexes · Updated Oct 1, 2025 · NCT06261463

About Post-Traumatic Stress Disorder

 You can get Post-Traumatic Stress Disorder (PTSD) after experiencing a traumatic event. PTSD starts at different times for different people.

More about Post-Traumatic Stress Disorder on MedlinePlus

Post-Traumatic Stress Disorder trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.