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Smoking clinical trials in Philadelphia, PA

6 studies for Smoking are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

RecruitingPhase 1Healthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 18 to 45 · All sexes · Updated Sep 24, 2026 · NCT03721822

Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 21 and older · All sexes · Updated Jun 11, 2026 · NCT07199517

A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers

RecruitingHealthy volunteers welcome
  • Sago Philadelphia, Philadelphia
Ages 21 to 65 · All sexes · Updated Jun 3, 2026 · NCT07598136

Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 21 and older · All sexes · Updated Mar 12, 2026 · NCT06372899

The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers

RecruitingHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
Ages 21 and older · All sexes · Updated Feb 19, 2026 · NCT06264154

Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates

RecruitingPhase 4
  • Corporal Michael J Crescenz VA Medical Center, Philadelphia
Ages 18 to 75 · All sexes · Updated Mar 22, 2019 · NCT03495024

About Smoking

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Smoking trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.