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Non-Small Cell Lung Cancer clinical trials in Aurora, CO

31 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Aurora (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Rocky Mountain Cancer Centers-Aurora, Aurora
  • UCHealth University of Colorado Hospital, Aurora
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • University of Colorado, Aurora
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06784193

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

RecruitingPhase 3
  • University of Colorado Anschutz Medical Campus ( Site 0151), Aurora
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06623422

A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)

RecruitingPhase 3
  • University of Colorado Cancer Center ( Site 3268), Aurora
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07513376

Symbiotic-Lung-20: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers

RecruitingPhase 1/2
  • Rocky Mountain Cancer Centers,LLP, Aurora
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07227298

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

RecruitingPhase 3
  • Clinical Study Site, Aurora
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06767514

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • University of Colorado - Aurora Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

RecruitingPhase 2/3
  • Local Institution - 007-872-H, Aurora
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04613596

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • University of Colorado, Aurora
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors

RecruitingPhase 1/2
  • UCHealth Cancer Center - Anschutz Medical Campus - University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06914128

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • University of Colorado Health Hospital, Aurora
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

RecruitingPhase 1
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06343402

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • University of Colorado, Aurora
Ages 18 to 99 · All sexes · Updated Sep 1, 2026 · NCT06983743

A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

RecruitingPhase 1/2
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06892548

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

RecruitingPhase 1
  • University of Colorado Hospital - Anschutz Cancer Pavilion (ACP), Aurora
  • University of Colorado Hospital, Aurora
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06131840

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • UCHealth University of Colorado Hospital, Aurora
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Response of Bony Metastasis to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers With Actionable Driver Mutations.

RecruitingObservational study
  • University of Colorado Hospital, Aurora
Ages 18 to 100 · All sexes · Updated Jun 3, 2026 · NCT03958565

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Rocky Mountain Regional VA Medical Center, Aurora
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06116682

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • UCHealth University of Colorado Hospital, Aurora
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

RecruitingPhase 1/2
  • University of Colorado Cancer Center, Aurora
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06362369

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Rocky Mountain Cancer Centers-Aurora, Aurora
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy

RecruitingObservational study
  • University of Colorado, Cancer Center, Aurora
Ages 18 to 85 · All sexes · Updated Feb 20, 2026 · NCT03042221

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Aurora
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers

RecruitingObservational study
  • University of Colorado Cancer Center at UC Health Sciences Center, Aurora
Ages 21 to 90 · All sexes · Updated Sep 22, 2025 · NCT00900419

A Study of NX-1607 in Adults With Advanced Malignancies

RecruitingPhase 1
  • University of Colorado School of Medicine, Aurora
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT05107674

Non-Small Cell Lung Cancer trials in other cities

Other studies in Aurora

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.