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Lung Cancer clinical trials in Springfield, IL
12 studies for Lung Cancer are looking for participants at sites in and around Springfield (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
RecruitingPhase 3
- Southern Illinois University School of Medicine, Springfield
- Springfield Clinic, Springfield
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
RecruitingObservational studyHealthy volunteers welcome
- Southern Illinois University School of Medicine, Springfield
- Springfield Clinic, Springfield
- Springfield Memorial Hospital, Springfield
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
RecruitingPhase 3
- Southern Illinois University School of Medicine, Springfield
- Springfield Clinic, Springfield
- Springfield Memorial Hospital, Springfield
Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer
RecruitingPhase 3
- Southern Illinois University School of Medicine, Springfield
- Springfield Clinic, Springfield
- Springfield Memorial Hospital, Springfield
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
RecruitingPhase 3
- Springfield Clinic Main Campus, Springfield
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
RecruitingPhase 3
- Southern Illinois University School of Medicine, Springfield
- Springfield Clinic, Springfield
- Springfield Memorial Hospital, Springfield
Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
RecruitingPhase 2
- Southern Illinois University School of Medicine, Springfield
- Springfield Clinic, Springfield
- Springfield Memorial Hospital, Springfield
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
RecruitingPhase 2
- Southern Illinois University School of Medicine, Springfield
- Springfield Clinic, Springfield
- Springfield Memorial Hospital, Springfield
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
RecruitingPhase 2/3
- Southern Illinois University School of Medicine, Springfield
- Springfield Clinic, Springfield
- Springfield Memorial Hospital, Springfield
Rural Illinois Lung Cancer Screening Initiative
RecruitingObservational study
- Sowmy Thuppal, Springfield
LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia
RecruitingObservational study
- Southern Illinois University School of Medicine, Springfield
- Springfield Clinic, Springfield
- Springfield Memorial Hospital, Springfield
Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening
RecruitingObservational study
- Springfield Clinic, LLP, Springfield
About Lung Cancer
Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.
More about Lung Cancer on MedlinePlus
Lung Cancer trials in other cities
- Houston, TX78 studies
- Boston, MA62 studies
- New York City, NY60 studies
- Los Angeles, CA45 studies
- Arlington, VA41 studies
- Washington, DC41 studies
- Chicago, IL41 studies
- Nashville, TN40 studies
- Baltimore, MD40 studies
- St. Louis, MO39 studies
- Columbus, OH37 studies
- Philadelphia, PA36 studies
Other studies in Springfield
- Non-Small Cell Lung Cancer13 studies
- Colorectal Cancer9 studies
- Acute Myeloid Leukemia8 studies
- Breast Cancer8 studies
- Head and Neck Squamous Cell Carcinoma6 studies
- Kidney Cancer (Renal Cell Carcinoma)6 studies
- Prostate Cancer6 studies
- Cancer (all types)6 studies
- Bladder Cancer6 studies
- Pancreatic Cancer5 studies
- Melanoma5 studies
- Multiple Myeloma4 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.