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Prostate Cancer clinical trials in Springfield, IL

6 studies for Prostate Cancer are looking for participants at sites in and around Springfield (within about 30 miles). Open a study to see who can join and how to contact the study team.

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT03866382

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

RecruitingPhase 3
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · Men · Updated Sep 2, 2026 · NCT06931340

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

RecruitingPhase 3
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Springfield Memorial Hospital, Springfield
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

RecruitingPhase 3
  • Southern Illinois University School of Medicine, Springfield
  • Springfield Clinic, Springfield
  • Memorial Medical Center, Springfield
Ages 18 and older · Men · Updated Jan 22, 2026 · NCT06470243

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Springfield

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.