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Pancreatic Cancer clinical trials in Baltimore, MD

31 studies for Pancreatic Cancer are looking for participants at sites in and around Baltimore (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Johns Hopkins University, Baltimore
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

RecruitingPhase 2/3
  • JHU Oncology Central Kit Services, Baltimore
  • Johns Hopkins Hospital, Baltimore
  • Oncology Investigational Drug Service (IDS), Baltimore
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 3
  • Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins & Sibley Memorial Hospital, Baltimore
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07252232

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

RecruitingPhase 3
  • University of Maryland School - Division of Hematology/Oncology, Baltimore
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07409272

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • The Sidney Kimmel Comprehensive Cancer Center at John Hopkins, Baltimore
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

RecruitingObservational study
  • The Johns Hopkins University School of Medicine, Baltimore
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06271291

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

RecruitingPhase 1
  • Johns Hopkins, Baltimore
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

RecruitingPhase 2
  • Johns Hopkins Hospital, Baltimore
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

RecruitingObservational study
  • Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore
Up to age 17 · All sexes · Updated Sep 11, 2026 · NCT06651580

Total Pancreatectomy With Islet Autotransplantation (TPIAT) for High-Risk Patients With Pancreatic Tumors

Recruiting
  • Johns Hopkins Hospital, Baltimore
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07360119

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

RecruitingPhase 2
  • Johns Hopkins University, Baltimore
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07644559

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

RecruitingPhase 3
  • Sinai Hospital of Baltimore, Baltimore
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06958328

Pancreatic Cancer Registry: For Any Person With a Personal or Family History

RecruitingObservational studyHealthy volunteers welcome
  • Johns Hopkins Hospital, Baltimore
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT02886247

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

RecruitingPhase 1
  • Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT06411691

EXoPERT EMERALD Clinical Study

RecruitingObservational studyHealthy volunteers welcome
  • John Hopkins University, Baltimore
Ages 45 and older · All sexes · Updated Jul 1, 2026 · NCT07186296

Mutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic Cancer

RecruitingPhase 1Healthy volunteers welcome
  • Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 40 and older · All sexes · Updated Jun 30, 2026 · NCT05013216

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Johns Hopkins University, Baltimore
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Johns Hopkins Hospital, Baltimore
Ages 18 and older · All sexes · Updated May 28, 2026 · NCT07223047

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

RecruitingPhase 3
  • Sinai Hospital of Baltimore, Baltimore
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06998940

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Johns Hopkins University, Baltimore
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

NC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metastatic Pancreatic Cancer

RecruitingPhase 2
  • Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06941857

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
  • Johns Hopkins University, Baltimore
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

Diagnostic Strategies, Risk Assessment and Progression of Pancreatic Cysts

RecruitingObservational study
  • The Johns Hopkins Hospital, Baltimore
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT04473794

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

RecruitingPhase 2
  • Ohio State University-Telemedicine, Baltimore
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT06906562

Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer

RecruitingPhase 1/2
  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Dec 3, 2025 · NCT06782932

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Baltimore
  • Massive Bio SYNERGY-AI site, Towson · 8 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

The Cancer of the Pancreas Screening-5 CAPS5)Study

RecruitingPhase 3
  • Johns Hopkins Hospital, Baltimore
Ages 18 and older · All sexes · Updated Oct 9, 2025 · NCT02000089

Confocal Laser Endomicroscopy as an Imaging Biomarker for the Diagnosis of Pancreatic Cystic Lesions

RecruitingObservational study
  • The Johns Hopkins Hospital, Baltimore
Ages 18 and older · All sexes · Updated Aug 22, 2025 · NCT03492151

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

RecruitingPhase 1/2
  • Johns Hopkins, Baltimore
Ages 18 and older · All sexes · Updated May 1, 2025 · NCT04503265

American Hepato-Pancreato-Biliary Association (AHPBA) Pancreatic Irreversible Electroporation (IRE) Registry

RecruitingObservational study
  • Johns Hopkins Hospital, Baltimore
Ages 18 and older · All sexes · Updated Feb 25, 2025 · NCT02674100

About Pancreatic Cancer

The pancreas is a gland behind your stomach that produces insulin. Pancreatic cancer is hard to catch early. Find out about risk factors and symptoms.

More about Pancreatic Cancer on MedlinePlus

Pancreatic Cancer trials in other cities

Other studies in Baltimore

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.