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Colorectal Cancer clinical trials in New Haven, CT

20 studies for Colorectal Cancer are looking for participants at sites in and around New Haven (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Yale Cancer Center, New Haven
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #62, New Haven
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

RecruitingPhase 1/2
  • Yale University School of Medicine, New Haven
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06324357

A Phase 1 Study of IM-1617 in Participants With Advanced Cancer

RecruitingPhase 1
  • Yale Cancer Center, New Haven
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07578571

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • Yale-New Haven Hospital-Yale Cancer Center, New Haven
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

RecruitingPhase 1
  • Yale Cancer Center, New Haven
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • Yale University School of Medicine - Yale Cancer Center, New Haven
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

RecruitingPhase 1
  • Yale Cancer Center, New Haven
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT04929223

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Clinical Study Site, New Haven
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

RecruitingPhase 2
  • Yale University, New Haven
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT06992258

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Yale University School of Medicine, New Haven
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

RecruitingPhase 1/2
  • Yale University, New Haven
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT05691491

A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors

RecruitingPhase 1/2
  • Yale Comprehensive Cancer Center, New Haven
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT07169734

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Smilow Cancer Hospital (Yale University), New Haven
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

RecruitingPhase 1
  • Yale University, New Haven
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06917079

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Yale University, Yale Cancer Center, New Haven
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in New Haven

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.