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Lupus clinical trials in New York City, NY

18 studies for Lupus are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

RecruitingPhase 2
  • Columbia University Medical Center, New York
Ages 18 to 75 · All sexes · Updated Oct 5, 2026 · NCT06570798

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
  • NYP/Weill Cornell Medical Center, New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT03816345

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

RecruitingPhase 3
  • Sl0044 50077, New York
Ages 16 and older · All sexes · Updated Oct 2, 2026 · NCT06617325

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

RecruitingPhase 3
  • Research Site, New York
Ages 5 to 17 · All sexes · Updated Sep 30, 2026 · NCT05835310

HEALTH Home Urinalysis Testing

Recruiting
  • NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07823478

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

RecruitingPhase 1/2
  • Research Site, New York
Ages 18 to 70 · All sexes · Updated Sep 10, 2026 · NCT06897930

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

RecruitingPhase 1
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 to 74 · All sexes · Updated Sep 10, 2026 · NCT07085104

Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)

RecruitingPhase 2
  • Icahn School of Medicine at Mount Sinai, New York
Ages 12 to 65 · All sexes · Updated Aug 24, 2026 · NCT07053800

Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease

RecruitingPhase 3
  • VA NY Harbor Healthcare System, New York
  • NYC Health + Hospitals/Bellevue, New York
  • NYU Langone Health, New York
  • and 2 more
Ages 55 and older · All sexes · Updated Aug 20, 2026 · NCT05799378

Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty

RecruitingPhase 2
  • NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT07138898

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus

RecruitingPhase 1
  • Columbia University Medical Center, New York
Ages 18 to 70 · All sexes · Updated Jun 5, 2026 · NCT06613360

A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

RecruitingPhase 1
  • Montefiore Medical Center, New York
Ages 12 to 70 · All sexes · Updated May 22, 2026 · NCT06308978

Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)

RecruitingObservational studyHealthy volunteers welcome
  • NYU Langone Medical Center/Hospital for Joint Diseases, New York
  • Hospital for Special Surgery, New York
Ages 18 to 45 · Women · Updated Apr 28, 2026 · NCT00198068

Alnuctamab for Refractory SLE (LATTE Study)

RecruitingPhase 1
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 to 60 · All sexes · Updated Apr 21, 2026 · NCT07219563

Lupus Landmark Study: A Prospective Registry and Biorepository

RecruitingObservational study
  • Columbia University Medical Center, New York
  • Northwell Health, New York
Ages 18 to 110 · All sexes · Updated Apr 15, 2026 · NCT05934149

Safety of the Herpes Zoster Subunit Vaccine in Lupus

RecruitingPhase 4
  • NYU Langone Health, New York
Ages 18 to 90 · All sexes · Updated Dec 26, 2025 · NCT05559671

Safety and Efficacy of ONT01 in Lupus

RecruitingEarly phase 1
  • Hospital for Special Surgery, New York
Ages 18 and older · All sexes · Updated Nov 20, 2025 · NCT07107659

About Lupus

Lupus is an autoimmune disease that causes your immune system to attack your healthy tissues and cells. This can cause damage to many parts of your body.

More about Lupus on MedlinePlus

Lupus trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.