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Lung Cancer clinical trials in Cincinnati, OH

19 studies for Lung Cancer are looking for participants at sites in and around Cincinnati (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Good Samaritan Hospital - Cincinnati, Cincinnati
  • Oncology Hematology Care Inc-Kenwood, Cincinnati
  • Bethesda North Hospital, Cincinnati
  • and 3 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

RecruitingPhase 3
  • University of Cincinnati Cancer Center-UC Medical Center, Cincinnati
  • University of Cincinnati Cancer Center-West Chester, West Chester · 15 mi away
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT04181060

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

RecruitingPhase 3
  • University of Cincinnati Cancer Center, Cincinnati
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06765109

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

RecruitingPhase 3
  • TriHealth Cancer & Blood Institute Research, Cincinnati
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06881784

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

RecruitingPhase 3
  • Saint Elizabeth Medical Center Edgewood-Cancer Care Center ( Site 0061), Edgewood · 8 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06312137

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Oncology Hematology Care Clinical Trials, Cincinnati
  • Oncology Hematology Care Clinical Trials, Cincinnati
  • Oncology Hematology Care Clinical Trials, Cincinnati
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

RecruitingPhase 2/3
  • The Christ Hospital Cancer Center, Cincinnati
  • University of Cincinnati Medical Center, Cincinnati
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06712316

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

RecruitingPhase 1/2
  • University of Cincinnati Cancer Center-UC Medical Center, Cincinnati
  • University of Cincinnati Cancer Center-West Chester, West Chester · 15 mi away
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06287775

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • USO - Oncology Hematology Care, Cincinnati
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

RecruitingPhase 3
  • The Christ Hospital Cancer Center, Cincinnati
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT06712355

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Xencor Investigative Site, Cincinnati
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 2
  • University of Cincinnati Medical Center, Cincinnati
Ages 18 to 70 · All sexes · Updated Jun 26, 2026 · NCT04614103

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • The Christ Hospital, Cincinnati
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

MYLUNG Consortium Part 3: Observational Study

RecruitingObservational study
  • Oncology Hematology Care Clinical Trials, LLC, Cincinnati
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT05885698

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Christ Hospital Cancer Center, Cincinnati
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Cincinnati
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study of Orally Administered JBI-802 Alone or in Combination With Pembrolizumab for Patients With Non-small Cell Lung Cancer With an STK11 Mutation.

RecruitingPhase 2
  • The Christ Hospital, Cincinnati
Ages 18 and older · All sexes · Updated Oct 6, 2025 · NCT07207395

Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier

RecruitingObservational study
  • University of Cincinnati, Cincinnati
Ages 29 to 85 · All sexes · Updated Nov 13, 2024 · NCT06426628

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Cincinnati

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.