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Prostate Cancer clinical trials in Cincinnati, OH

18 studies for Prostate Cancer are looking for participants at sites in and around Cincinnati (within about 30 miles). Open a study to see who can join and how to contact the study team.

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

RecruitingPhase 3
  • TriState Urologic Services PSC Inc. dba The Urology Group, Cincinnati
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07028853

A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 3
  • Oncology Hematology Care Incorporated, Cincinnati
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

RecruitingPhase 3
  • Urology Group - Solaris Network, Cincinnati
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277

Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 1
  • Oncology Hematology Care Incorporated, Cincinnati
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07493512

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

RecruitingPhase 2
  • Solaris Health - The Urology Group, Cincinnati
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07005154

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Good Samaritan Hospital - Cincinnati, Cincinnati
  • Oncology Hematology Care Inc-Kenwood, Cincinnati
  • Bethesda North Hospital, Cincinnati
  • and 3 more
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

RecruitingPhase 2
  • Saint Elizabeth Healthcare Edgewood, Edgewood · 8 mi away
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06632977

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1
  • Oncology Hematology Care Incorporated, Cincinnati
Ages 18 and older · Men · Updated Aug 21, 2026 · NCT04221542

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

RecruitingPhase 3
  • Good Samaritan Hospital - Cincinnati, Cincinnati
  • Bethesda North Hospital, Cincinnati
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

RecruitingPhase 1
  • University of Cincinnati Medical Center, Cincinnati
Ages 18 to 100 · Men · Updated Aug 13, 2026 · NCT05519449

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3
  • Good Samaritan Hospital - Cincinnati, Cincinnati
  • Bethesda North Hospital, Cincinnati
  • TriHealth Cancer Institute-Westside, Cincinnati
  • and 1 more
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Prostate Ablation Registry and Database for Information, Surveillance, and Evaluation (PARADISE)

RecruitingObservational study
  • The University of Cinncinatti, Cincinnati
Ages 22 and older · Men · Updated Feb 2, 2026 · NCT06705803

Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

RecruitingPhase 2
  • Good Samaritan Hospital - Cincinnati, Cincinnati
  • Bethesda North Hospital, Cincinnati
  • TriHealth Cancer Institute-Westside, Cincinnati
  • and 1 more
Ages 18 and older · Men · Updated Jan 29, 2026 · NCT05806515

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 113, Cincinnati
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Cincinnati
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3
  • University of Cincinnati Cancer Center-UC Medical Center, Cincinnati
  • University of Cincinnati Cancer Center-West Chester, West Chester · 15 mi away
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

Real World Prostate Cancer Registry

RecruitingObservational study
  • Cincinnati Cancer Advisors, Cincinnati
Ages 18 and older · Men · Updated May 31, 2025 · NCT06355336

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Cincinnati

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.