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Alzheimer's Disease clinical trials in Nashville, TN

10 studies for Alzheimer's Disease are looking for participants at sites in and around Nashville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Randomized Study to Evaluate the Effect of Obicetrapib in Participants With Preclinical Alzheimer's Disease

RecruitingPhase 2
  • K2 Medical Research, Nashville
Ages 55 to 85 · All sexes · Updated Sep 28, 2026 · NCT07794670

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

RecruitingPhase 3
  • Vanderbilt Psychiatric Hospital, Nashville
Ages 55 to 90 · All sexes · Updated Sep 22, 2026 · NCT06585787

Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

RecruitingPhase 2
  • K2 Medical Research Nashville LLC, Nashville
Ages 55 to 80 · All sexes · Updated Sep 21, 2026 · NCT06847321

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

RecruitingPhase 3
  • K2 Medical Research - Nashville, Nashville
Ages 50 to 90 · All sexes · Updated Sep 21, 2026 · NCT07177352

Alzheimer's Tau Platform: Master Protocol

RecruitingPhase 2
  • Vanderbilt University Medical Center, Nashville
Ages 50 to 80 · All sexes · Updated Sep 8, 2026 · NCT06957418

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

RecruitingPhase 2
  • Vanderbilt University Medical Center- Village, Nashville
Ages 55 to 90 · All sexes · Updated Sep 1, 2026 · NCT06808984

Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

RecruitingPhase 2Healthy volunteers welcome
  • Vanderbilt University Medical Center Clinical Research Center, Nashville
Ages 18 to 55 · All sexes · Updated Jun 22, 2026 · NCT05231798

Trial-Ready Cohort-Down Syndrome (TRC-DS)

RecruitingObservational study
  • Vanderbilt University Medical Center Center for Cognitive Medicine, Nashville
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109

Swallowing Impairments in Adults With and Without Alzheimer's Disease

RecruitingObservational studyHealthy volunteers welcome
  • Vanderbilt University Medical Center, Nashville
Ages 60 and older · All sexes · Updated May 8, 2026 · NCT06678100

Tennessee Alzheimer's Project

RecruitingObservational studyHealthy volunteers welcome
  • Vanderbilt University Medical Center, Nashville
Ages 60 and older · All sexes · Updated Feb 5, 2026 · NCT05372172

About Alzheimer's Disease

Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills. It's the most common cause of dementia among older adults.

More about Alzheimer's Disease on MedlinePlus

Alzheimer's Disease trials in other cities

Other studies in Nashville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.