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Autoimmune Diseases clinical trials in Durham, NC

15 studies for Autoimmune Diseases are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Environmental Risk Factors for the Anti-synthetase Syndrome

RecruitingObservational studyHealthy volunteers welcome
  • NIEHS Clinical Research Unit (CRU), Research Triangle Park · 7 mi away
Ages 2 to 100 · All sexes · Updated Sep 28, 2026 · NCT01276470

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

RecruitingPhase 3
  • Duke University Hospital, Durham
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06722235

RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy

RecruitingPhase 2/3
  • Duke University Medical Center - Accepting Young Adults and Juvenile Patients, Durham
  • University of North Carolina at Chapel Hill - Accepting Adult Patients, Chapel Hill · 10 mi away
Ages 6 to 75 · All sexes · Updated Sep 17, 2026 · NCT06154252

Daratumumab in Primary Antiphospholipid Syndrome

RecruitingPhase 1/2
  • Duke University, Durham
Ages 18 to 65 · All sexes · Updated Sep 16, 2026 · NCT05671757

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

RecruitingPhase 1
  • Duke University Medical Center, Durham
Ages 18 to 74 · All sexes · Updated Sep 10, 2026 · NCT07085104

A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

RecruitingPhase 3
  • Duke University Hospital, Durham
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06948318

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

RecruitingPhase 3
  • GSK Investigational Site, Durham
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06572384

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

RecruitingPhase 1/2
  • UNC Chapel Hill, Chapel Hill · 10 mi away
Ages 18 to 65 · All sexes · Updated Aug 26, 2026 · NCT06121297

RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

RecruitingPhase 2/3
  • Duke University, Durham
Ages 18 to 75 · All sexes · Updated Aug 17, 2026 · NCT06328777

Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis

RecruitingPhase 3
  • Site Number - 1013, Durham
  • Site Number - 1020, Chapel Hill · 10 mi away
Ages 18 to 80 · All sexes · Updated Jul 30, 2026 · NCT07039916

A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases

RecruitingPhase 1
  • Duke University, Durham
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT07115745

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

RecruitingObservational study
  • Duke University Medical Center, Durham
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
All ages · All sexes · Updated Jul 6, 2026 · NCT01351545

A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

RecruitingPhase 1
  • Duke University Health System, Durham
Ages 12 to 70 · All sexes · Updated May 22, 2026 · NCT06308978

Maternal Autoimmune Disease Research Alliance (MADRA) Registry

RecruitingObservational studyHealthy volunteers welcome
  • Duke University, Durham
All ages · Women · Updated Jan 8, 2026 · NCT03276923

About Autoimmune Diseases

Autoimmune diseases are where your immune system attacks healthy cells in your body by mistake. Learn about the symptoms, tests, and treatments.

More about Autoimmune Diseases on MedlinePlus

Autoimmune Diseases trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.