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Colorectal Cancer clinical trials in Grand Rapids, MI

40 studies for Colorectal Cancer are looking for participants at sites in and around Grand Rapids (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07454642

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

RecruitingPhase 2
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07659795

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics (START), Grand Rapids
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids
  • Trinity Health Grand Rapids Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

RecruitingPhase 1/2
  • BAMF Health, Grand Rapids
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07189871

A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors

RecruitingPhase 1
  • ALX Center 3, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07085091

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • The Cancer & Hematology Centers, Grand Rapids
  • The Cancer & Hematology Centers, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

RecruitingPhase 3
  • Cancer And Hematology Centers of Western Michigan PC, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06750094

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

RecruitingPhase 1
  • Start Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06663319

A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06004245

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

RecruitingPhase 3
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

RecruitingPhase 2
  • Research Site, Grand Rapids
Ages 18 to 130 · All sexes · Updated Sep 23, 2026 · NCT05489211

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

RecruitingPhase 1
  • BAMF Health Inc., Grand Rapids
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

RecruitingPhase 1
  • BAMF Health Inc., Grand Rapids
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

RecruitingPhase 3
  • Cancer and Hematology Centers of Western Michigan, Grand Rapids
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06252649

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06586515

A Study of MGC026 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

RecruitingPhase 1
  • BAMF Health, Grand Rapids
Ages 18 to 100 · All sexes · Updated Jul 29, 2026 · NCT06562192

A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06131840

A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • START Midwest, LLC, Grand Rapids
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07318805

CT-95 in Advanced Cancers Associated With Mesothelin Expression

RecruitingPhase 1
  • Context Investigational Site, Grand Rapids
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06756035

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT07094204

A Study of MGC028 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT06723236

A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

RecruitingPhase 1
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT06720987

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids
  • Trinity Health Grand Rapids Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Trinity Health Grand Rapids Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • START Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors

RecruitingPhase 1/2
  • START, Midwest, Grand Rapids
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT07145255

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

RecruitingObservational study
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids
  • Trinity Health Grand Rapids Hospital, Grand Rapids
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer

RecruitingPhase 1/2
  • BAMF Health, Inc., Grand Rapids
Ages 15 and older · All sexes · Updated Aug 12, 2025 · NCT06298916

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Grand Rapids

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.