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Head and Neck Squamous Cell Carcinoma clinical trials in Cincinnati, OH

14 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Cincinnati (within about 30 miles). Open a study to see who can join and how to contact the study team.

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

RecruitingPhase 2/3
  • Site#0117, Cincinnati
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

RecruitingPhase 3
  • University of Cincinnati, Cincinnati
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07276399

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

RecruitingPhase 3
  • University of Cincinnati, Cincinnati
Ages 60 and older · All sexes · Updated Sep 25, 2026 · NCT04892173

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

RecruitingPhase 2
  • University of Cincinnati Cancer Center-UC Medical Center, Cincinnati
  • University of Cincinnati Cancer Center-West Chester, West Chester · 15 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06980038

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

RecruitingPhase 2
  • University of Cincinnati Cancer Center-UC Medical Center, Cincinnati
  • Good Samaritan Hospital - Cincinnati, Cincinnati
  • Oncology Hematology Care Inc-Kenwood, Cincinnati
  • and 4 more
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

RecruitingObservational study
  • University of Cincinnati, Cincinnati
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • St. Elizabeth Healthcare, Edgewood · 8 mi away
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06769698

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

RecruitingPhase 2
  • University of Cincinnati Cancer Center-UC Medical Center, Cincinnati
  • University of Cincinnati Cancer Center-West Chester, West Chester · 15 mi away
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06532279

Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin

RecruitingPhase 3
  • University of Cincinnati Cancer Center-UC Medical Center, Cincinnati
  • University of Cincinnati Cancer Center-West Chester, West Chester · 15 mi away
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07441681

Phase I/ II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma

RecruitingPhase 1/2
  • University of Cincinnati Medical Center, Cincinnati
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT07213934

Reduced Elective Nodal and CTV Dose for HPV+ Oropharyngeal Squamous Cell Carcinoma

RecruitingPhase 2
  • University of Cincinnati Medical Center, Cincinnati
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT07497607

A Study of DB-1310 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Carl & Edyth Lindner Center for Research & Education at The Christ Hospital and The Christ Hospital Cancer Center, Cincinnati
Ages 18 and older · All sexes · Updated Apr 6, 2026 · NCT05785741

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 113, Cincinnati
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

RecruitingPhase 1/2
  • The Christ Hospital, Cincinnati
Ages 18 and older · All sexes · Updated Nov 4, 2025 · NCT05902988

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Cincinnati

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.