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Parkinson's Disease clinical trials in Chicago, IL

13 studies for Parkinson's Disease are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

RecruitingPhase 2
  • Northwestern Medical Group, Department of Neurology, Chicago
Ages 40 to 80 · All sexes · Updated Oct 2, 2026 · NCT06680830

A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease

RecruitingPhase 1Healthy volunteers welcome
  • Northwestern University Feinberg School of Medicine Dept of Neurology, Chicago
Ages 30 to 80 · All sexes · Updated Oct 1, 2026 · NCT06565195

A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease

RecruitingPhase 2/3
  • Site-027, Chicago
Ages 40 to 80 · All sexes · Updated Sep 28, 2026 · NCT06976268

GBPDC: Gut-Brain in PD Consortium Master Protocol

RecruitingObservational studyHealthy volunteers welcome
  • Rush University, Chicago
  • University of Chicago, Chicago
Ages 21 to 80 · All sexes · Updated Sep 25, 2026 · NCT07567794

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

RecruitingObservational study
  • Rush University Medical Center, Chicago
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT02071134

Parkinson's Foundation PD GENEration Genetic Registry

RecruitingObservational study
  • University of Illinois-Chicago, Chicago
  • Rush University, Chicago
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04994015

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

RecruitingPhase 3
  • Northwestern University Feinberg School Of Medicine, Chicago
Ages 50 to 85 · All sexes · Updated Sep 3, 2026 · NCT07174310

A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

RecruitingPhase 3
  • Parkinson's Disease and Movement Disorders Center at Northwestern Memorial Hospital, Chicago
  • Rush University Medical Center - Neurology, Chicago
Ages 45 to 75 · All sexes · Updated Aug 4, 2026 · NCT06944522

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Northwestern University, Chicago
Ages 30 and older · All sexes · Updated Jul 27, 2026 · NCT04477785

Use of CereGate Therapy for Freezing of Gait in PD

Recruiting
  • Northwestern University, Chicago
Ages 21 to 80 · All sexes · Updated May 28, 2026 · NCT05292794

rTMS to Improve Cognition in Parkinson's

RecruitingPhase 1/2
  • Jesse Brown VA Medical Center, Chicago, IL, Chicago
Ages 50 and older · All sexes · Updated Apr 21, 2026 · NCT03836950

Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

RecruitingObservational studyHealthy volunteers welcome
  • Rush University, Chicago
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Feb 27, 2026 · NCT06719583

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

RecruitingObservational study
  • Rush University Medical Center, Chicago
All ages · All sexes · Updated Jan 8, 2026 · NCT04071847

About Parkinson's Disease

Parkinson's disease (PD) is a movement disorder. It causes tremors, stiffness, and slow movement. It gets worse over time. Learn what can help.

More about Parkinson's Disease on MedlinePlus

Parkinson's Disease trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.