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Prostate Cancer clinical trials in Madison, WI

29 studies for Prostate Cancer are looking for participants at sites in and around Madison (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of Wisconsin Carbone Cancer Center, Madison
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

RecruitingPhase 3
  • William S Middleton VA Medical Center, Madison
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT06931340

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • William S Middleton VA Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

PET/CT Characterization of Treatment Resistance

Recruiting
  • University of Wisconsin, Madison
Ages 18 and older · Men · Updated Oct 1, 2026 · NCT05647564

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

RecruitingPhase 3
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07028853

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

RecruitingPhase 2
  • William S. Middleton Memorial Veterans Hospital, Madison, WI, Madison
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT05011383

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

RecruitingPhase 2
  • William S. Middleton Memorial Veterans Hospital, Madison, WI, Madison
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT04038502

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

RecruitingPhase 3
  • University Hospital and UW Health Clinics ( Site 0065), Madison
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)

RecruitingPhase 2
  • Carbone Cancer Center University of Wisconsin-Madison, Madison
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT06150417

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

RecruitingPhase 3
  • University of Wisconsin, Madison
Ages 18 and older · Men · Updated Sep 11, 2026 · NCT06056830

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

RecruitingPhase 2
  • UW Health Carbone Cancer Center, Madison
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07005154

COMPASS Study for Metastatic Castration-resistant Prostate Cancer

RecruitingObservational study
  • University of Wisconsin Carbone Cancer Center, Madison
Ages 18 and older · Men · Updated Aug 27, 2026 · NCT07050433

A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide

RecruitingPhase 2
  • University of Wisconsin Carbone Cancer Center-Madison, Madison
Ages 18 and older · Men · Updated Aug 21, 2026 · NCT06844383

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

RecruitingPhase 3
  • William S Middleton VA Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of Wisconsin, Carbone Cancer Center, Madison
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

RecruitingPhase 1
  • University of Wisconsin Carbone Cancer Center, Madison
Ages 18 to 100 · Men · Updated Aug 13, 2026 · NCT05519449

Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

RecruitingObservational study
  • University of Wisconsin-Madison, Madison
Ages 18 and older · Men · Updated Aug 12, 2026 · NCT04489719

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

RecruitingPhase 2
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT05691465

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

RecruitingPhase 1
  • University of Wisconsin, Madison
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT07103018

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

RecruitingPhase 1
  • University of Wisconsin Carbone Cancer Center, Madison
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT05413421

Using FAPI PET/MRI to Evaluate Prostate Cancer

RecruitingPhase 2
  • University of Wisconsin, Madison
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06675357

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

RecruitingObservational study
  • University of Wisconsin Carbone Cancer Center, Madison
Ages 21 and older · Men · Updated May 22, 2026 · NCT03151629

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

RecruitingPhase 2/3
  • William S. Middleton Memorial Veterans Hospital, Madison, WI, Madison
Ages 18 and older · Men · Updated Apr 8, 2026 · NCT04787744

Novel ACK1 Inhibitor (R)-9b in Patients With Prostate Cancer

RecruitingPhase 1
  • University of Wisconsin Carbone Cancer Center (UWCCC) - Cancer Connect, Madison
Ages 18 and older · Men · Updated Mar 20, 2026 · NCT06705686

Trial of pTVG-HP+Nivo+Targeted Ablation of Resistant Lesions in Non-Castrate RecurrentOMPC

RecruitingPhase 1
  • University of Wisconsin - Madison, Madison
Ages 18 and older · Men · Updated Mar 11, 2026 · NCT07090148

Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

RecruitingPhase 4
  • University of Wisconsin, Madison
Ages 18 to 64 · All sexes · Updated Jan 22, 2026 · NCT04373564

ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials

RecruitingObservational study
  • University of Wisconsin-Madison, Madison
Ages 18 and older · Men · Updated Oct 15, 2025 · NCT06141993

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

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Other studies in Madison

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.