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Healthy volunteer studies in Portland, OR

67 studies at sites in and around Portland accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Providence Portland Medical Center, Portland
  • Providence Saint Vincent Medical Center, Portland
  • Providence Willamette Falls Medical Center, Oregon City · 12 mi away
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

RecruitingHealthy volunteers welcome
  • Providence Portland Medical Center, Portland
  • Providence Saint Vincent Medical Center, Portland
  • Providence Willamette Falls Medical Center, Oregon City · 12 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07091617

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Providence Portland Medical Center, Portland
  • Providence Saint Vincent Medical Center, Portland
  • Providence Willamette Falls Medical Center, Oregon City · 12 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487

Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure

RecruitingObservational studyHealthy volunteers welcome
  • Decentralized / At-Home Participation (U.S.), Portland
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07775495

Clinical Outcomes and Pharmacotherapy Effectiveness in the VA Health Care System (COPE-VA)

RecruitingObservational studyHealthy volunteers welcome
  • VA Portland Health Care System, Portland, OR, Portland
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06160128

Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)

RecruitingPhase 3Healthy volunteers welcome
  • VA Portland Health Care System, Portland, OR, Portland
Ages 18 to 80 · All sexes · Updated Sep 21, 2026 · NCT07218354

A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Portland
Ages 65 and older · All sexes · Updated Sep 18, 2026 · NCT07805707

Connect for Cancer Prevention Study (Connect)

RecruitingObservational studyHealthy volunteers welcome
  • Kaiser Permanente Northwest, Portland
Ages 30 to 70 · All sexes · Updated Sep 17, 2026 · NCT04609072

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Portland
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

Functional and Structural Imaging for Glaucoma

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Casey Eye Institute, Portland
Ages 40 to 85 · All sexes · Updated Sep 9, 2026 · NCT01957267

A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

RecruitingPhase 3Healthy volunteers welcome
  • Kaiser Permanente Center for Health Research, Portland
Ages 65 and older · All sexes · Updated Sep 9, 2026 · NCT07282665

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health and Science University, Portland
4 Weeks · All sexes · Updated Sep 2, 2026 · NCT03739827

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

An Exercise Intervention for Improving Mental and Physical Health in Patients With Primary Brain Tumors and Their Caregivers, ET-NEURO Trial

RecruitingHealthy volunteers welcome
  • OHSU Knight Cancer Institute, Portland
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07278440

The HOPE Biobank Resource (BMT CTN 2402 HOPE)

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health and Science University, Portland
All ages · All sexes · Updated Aug 27, 2026 · NCT07227155

ASSESS ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Providence ALS Center, Portland
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06578195

PREVENT ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Providence ALS Center, Portland
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06581861

Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis

RecruitingPhase 4Healthy volunteers welcome
  • VA Portland Health Care System, Portland, OR, Portland
Ages 40 and older · All sexes · Updated Aug 19, 2026 · NCT04373317

Sleep Duration and Cardiovascular Health

RecruitingHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 25 to 65 · All sexes · Updated Aug 4, 2026 · NCT04804124

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health &Science University, Portland
Ages 30 and older · All sexes · Updated Jul 27, 2026 · NCT04477785

Pancreatic Cancer Early Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

Comprehensive HHT Outcomes Registry of the United States (CHORUS)

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health and Science University, Portland
All ages · All sexes · Updated Jul 17, 2026 · NCT06259292

Identifying and Caring for Individuals With Inherited Cancer Syndrome

RecruitingHealthy volunteers welcome
  • Providence Portland Medical Center, Portland
  • OHSU Knight Cancer Institute, Portland
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT04494945

Disparities in Emergency Contraceptive Metabolism Dictate Efficacy

RecruitingPhase 4Healthy volunteers welcome
  • OHSU, Portland
Ages 18 to 40 · Women · Updated Jul 9, 2026 · NCT05674513

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 15 to 55 · Women · Updated Jun 4, 2026 · NCT06030063

Galleri® in the Medicare Population.

RecruitingHealthy volunteers welcome
  • OHSU CEDAR Clinical Trials Portland, Portland
  • OHSU CEDAR Clinical Trials Richmond, Portland
Ages 50 and older · All sexes · Updated May 22, 2026 · NCT05673018

Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

RecruitingObservational studyHealthy volunteers welcome
  • OHSU Knight Cancer Institute, Portland
Ages 40 and older · Men · Updated May 15, 2026 · NCT04472338

Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking

RecruitingHealthy volunteers welcome
  • Portland State University, Portland
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT06501677

Mediators and Moderators of Auditory Training

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 85 · All sexes · Updated Apr 20, 2026 · NCT06812273

Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits

RecruitingPhase 4Healthy volunteers welcome
  • VA Portland Health Care System, Portland, OR, Portland
Ages 18 and older · All sexes · Updated Apr 20, 2026 · NCT04419272

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Providence Portland Medical Center, Portland
  • Providence Saint Vincent Medical Center, Portland
  • Providence Willamette Falls Medical Center, Oregon City · 12 mi away
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Beat Childhood Cancer Specimen Banking and Data Registry

RecruitingObservational studyHealthy volunteers welcome
  • Randall Children's Hospital, Portland
All ages · All sexes · Updated Feb 3, 2026 · NCT04715178

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
All ages · All sexes · Updated Feb 2, 2026 · NCT04005976

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health Sciences University, Portland
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT05677880

Insights in Endocervical Mucus Secretion

RecruitingPhase 4Healthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 21 to 40 · Women · Updated Jan 8, 2026 · NCT07111247

CGM for the Early Detection and Management of Hyperglycemia in Pregnancy

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 and older · Women · Updated Dec 23, 2025 · NCT06957028

Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Doernbecher Children's Hospital, Portland
All ages · All sexes · Updated Dec 12, 2025 · NCT00950118

The Influence of Sleep on Cardiovascular Outcomes

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 50 · All sexes · Updated Nov 10, 2025 · NCT06535178

Food and Circadian Timing

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 40 · All sexes · Updated Nov 10, 2025 · NCT04743271

STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partners

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 100 · All sexes · Updated Oct 27, 2025 · NCT06613204

Support Via Technology: Living and Learning With Advancing Dementia-REVISED

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Layton Aging and Alzheimer's Disease Research Center, Portland
Ages 18 and older · All sexes · Updated Oct 23, 2025 · NCT06460012

Comparative Effectiveness of Cryoablation Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma

RecruitingHealthy volunteers welcome
  • Oregon Health Sciences University, Portland
Ages 18 to 105 · All sexes · Updated Oct 16, 2025 · NCT05501262

Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 5 to 62 · Men · Updated Oct 15, 2025 · NCT01484678

OCT Angiography and NRAI in Dementia

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 55 and older · All sexes · Updated Sep 12, 2025 · NCT03761381

Observational Study of Iris Tumors

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT03809585

OCT in Diagnosis of Irregular Corneas

RecruitingObservational studyHealthy volunteers welcome
  • Humberto Martinez, Portland
Ages 14 to 85 · All sexes · Updated Sep 9, 2025 · NCT03504800

Effect of Abdominal Wall Injections on Abdominal Pain

RecruitingPhase 4Healthy volunteers welcome
  • OHSU, Portland
  • Oregon Health Sciences University, Portland
Ages 18 to 100 · All sexes · Updated Sep 2, 2025 · NCT06121466

Immunogenicity of Yellow Fever Vaccine 17D in Adults With Prior 17D Vaccination

RecruitingPhase 1/2Healthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 20 to 49 · All sexes · Updated Jul 31, 2025 · NCT05859490

Effects of a Specific Substance in Smokers

RecruitingHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 21 to 40 · All sexes · Updated Jul 28, 2025 · NCT04281979

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 120 · All sexes · Updated Jul 25, 2025 · NCT05237258

Quantification & Classification of Inflammatory Cells in Uveitis Using OCT

RecruitingObservational studyHealthy volunteers welcome
  • Casey Eye Institute - Oregon Health & Science University, Portland
Ages 5 to 85 · All sexes · Updated Jul 17, 2025 · NCT07065747

EMBRACE: Exercising Together

RecruitingPhase 2Healthy volunteers welcome
  • OHSU Knight Cancer Institute, Portland
Ages 18 and older · All sexes · Updated May 29, 2025 · NCT06049355

Diet and Active Lifestyle - Yuuyaraq (The Yup'ik Way of Life)

RecruitingHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 18 and older · All sexes · Updated May 7, 2025 · NCT06629610

The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

RecruitingHealthy volunteers welcome
  • OHSU, Portland
Ages 18 and older · All sexes · Updated Apr 11, 2025 · NCT05564936

Focus Groups in Ethnically and Racially Diverse Families

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 80 · All sexes · Updated Apr 4, 2025 · NCT05930886

Endometrial Biopsy in Progestin Contraceptive Users

RecruitingEarly phase 1Healthy volunteers welcome
  • OHSU, Portland
Ages 18 to 40 · Women · Updated Mar 20, 2025 · NCT05760144

Monoferric for Prenatal Iron Deficiency

RecruitingEarly phase 1Healthy volunteers welcome
  • Oregon Health & Science Univerity, Portland
Ages 18 to 65 · Women · Updated Sep 19, 2024 · NCT05763043

Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use Disorder

RecruitingPhase 4Healthy volunteers welcome
  • VA Portland Health Care System, Portland
Ages 18 to 60 · All sexes · Updated Jul 18, 2024 · NCT06426303

The Parkinson's Genetic Research Study

RecruitingObservational studyHealthy volunteers welcome
  • Portland VA Medical Center, Portland
Ages 18 and older · All sexes · Updated May 14, 2024 · NCT01558479

Reaching Out to Distressed Medical Residents, Fellows and Faculty

RecruitingHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 18 and older · All sexes · Updated Apr 30, 2024 · NCT02010866

Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study

RecruitingPhase 4Healthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 70 to 110 · All sexes · Updated Apr 8, 2024 · NCT06036095

Sleep and Metabolism

RecruitingHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Ages 18 to 40 · All sexes · Updated Apr 3, 2024 · NCT05775627

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health and Science University, Portland
Ages 18 and older · All sexes · Updated Feb 28, 2024 · NCT01574053

OCT Angiography in Wet AMD

RecruitingObservational studyHealthy volunteers welcome
  • Casey Eye Institute, Oregon Health & Science University, Portland
Ages 50 to 100 · All sexes · Updated Feb 12, 2024 · NCT02253030

Clinical and Genetic Analysis of ROP

RecruitingObservational studyHealthy volunteers welcome
  • Oregon Health & Science University, Portland
Up to age 1 · All sexes · Updated Apr 20, 2022 · NCT04420156

Augmentation of Limb Perfusion With Contrast Ultrasound

RecruitingHealthy volunteers welcome
  • OHSU, Portland
Ages 19 to 99 · All sexes · Updated Aug 23, 2018 · NCT03195556

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.