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Chronic Pain clinical trials in Boston, MA

17 studies for Chronic Pain are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06094257

RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

RecruitingObservational study
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT01719055

Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study

Recruiting
  • Massachusetts General Hospital, Boston
Ages 50 to 120 · All sexes · Updated Aug 25, 2026 · NCT07118722

From Nerve to Brain: Toward a Mechanistic Understanding of Spinal Cord Stimulation in Human Subjects

RecruitingPhase 2
  • Massachusetts General Hospital, Boston
  • Beth Israel Deaconess Medical Center, Boston
  • Brigham and Women's Hospital, Boston
Ages 18 to 80 · All sexes · Updated Aug 20, 2026 · NCT05661903

Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome

Recruiting
  • Spaulding Rehabilitation Network Research Institute, Charlestown · 1 mi away
Ages 18 to 80 · All sexes · Updated Aug 18, 2026 · NCT04206215

Screening Trial for Pain Relief in Schwannomatosis (STARFISH)

RecruitingPhase 2
  • Massachusetts General Hospital Cancer Center, Boston
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT05684692

Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline

Recruiting
  • Massachusetts General Hospital, Boston
Ages 50 and older · All sexes · Updated Jul 7, 2026 · NCT06246929

CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial

RecruitingPhase 3
  • Harvard University- Brigham and Women's Hospital, Boston
Ages 18 to 75 · All sexes · Updated May 6, 2026 · NCT06027099

Adolescent Outcomes of Post-operative Opioid EXposure

RecruitingObservational study
  • Boston Childrens Hopsital - Division of Addiction Medicine, Boston
Ages 12 to 17 · All sexes · Updated Mar 18, 2026 · NCT06350409

Mind Body Intervention for Chronic Migraine Headaches

Recruiting
  • Beth Israel Deaconess Medical Center, Boston
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06690060

Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Mar 13, 2026 · NCT06991205

Mind Body Intervention for Chronic Upper Extremity Pain (Repetitive Stress Injury)

Recruiting
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 to 60 · All sexes · Updated Feb 18, 2026 · NCT06903962

fMRI and IVCM Cornea Microscopy of CXL in Keratoconus

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 8 to 35 · All sexes · Updated Dec 19, 2025 · NCT04439552

Group Medical Visits and Chiropractic Care for Older Adults With Chronic Spine Pain

Recruiting
  • MassGeneralBrigham, Boston
Ages 65 and older · All sexes · Updated Nov 26, 2025 · NCT06632535

Improving Health for Older Adults With Pain Through Engagement

Recruiting
  • Massachusetts General Hospital, Boston
Ages 55 and older · All sexes · Updated Nov 18, 2025 · NCT06119698

Cognitive Training to Enhance Brain Concordance During Acupuncture

Recruiting
  • Massachusetts General Hospital, Charlestown · 1 mi away
  • Spaulding Rehabilitation Hospital, Charlestown · 1 mi away
Ages 18 to 65 · All sexes · Updated Oct 24, 2025 · NCT06157866

iCanCope With Post-Operative Pain (iCanCope PostOp)

Recruiting
  • Boston Children's Hospital, Boston
Ages 12 to 18 · All sexes · Updated Jul 9, 2025 · NCT05382962

About Chronic Pain

Chronic pain lasts longer than three months or the time in which you should have healed. It is not always curable, but treatments can help.

More about Chronic Pain on MedlinePlus

Chronic Pain trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.