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Colorectal Cancer clinical trials in Austin, TX

19 studies for Colorectal Cancer are looking for participants at sites in and around Austin (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • New Experimental Therapeutics - NEXT Oncology, Austin
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • NEXT Austin, Austin
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #46, Austin
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

RecruitingPhase 3
  • Ascension Seton Spclty Care Ctr, Austin
  • Texas Oncology, Austin
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

RecruitingPhase 1
  • NEXT Austin, Austin
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07227168

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Texas Oncology - Central/South Texas, Austin
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Texas Oncology - Central South, Austin
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144

A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

RecruitingPhase 1
  • NEXT Texas LLC - Austin, Austin
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT07503808

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Texas LLC - Austin, Austin
Ages 18 to 99 · All sexes · Updated Jun 16, 2026 · NCT07540572

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

RecruitingPhase 2
  • Texas Oncology - Central/South Texas, Austin
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07011576

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • University of Texas at Austin, Austin
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology, Austin, TX 78758
Ages 18 and older · All sexes · Updated Apr 2, 2026 · NCT06451497

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Elligo Health Research, Inc., Austin
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

Evaluation of the Natera Colorectal Cancer Screening Test in an Average Risk Population (FIND-CRC)

RecruitingObservational studyHealthy volunteers welcome
  • Natera, Inc, Austin
Ages 40 and older · All sexes · Updated Dec 12, 2025 · NCT07046585

Prospective Collection of Samples to Enable the Development of Natera Screening Assay for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Natera, Austin
Ages 40 and older · All sexes · Updated Jan 29, 2025 · NCT06620627

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Austin

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.