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Esophageal Adenocarcinoma clinical trials in Philadelphia, PA

8 studies for Esophageal Adenocarcinoma are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

RecruitingPhase 2/3
  • Thomas Jefferson University Hospital, Philadelphia
  • Jefferson Torresdale Hospital, Philadelphia
  • Asplundh Cancer Pavilion, Willow Grove · 13 mi away
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06203600

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

RecruitingPhase 3
  • Thomas Jefferson University Hospital, Philadelphia
  • Einstein Medical Center Philadelphia, Philadelphia
  • Asplundh Cancer Pavilion, Willow Grove · 13 mi away
  • and 2 more
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05677490

Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

RecruitingPhase 2/3
  • Alliance Cancer Specialists, PC, Wynnewood · 7 mi away
  • Alliance Cancer Specialists, PC, Media · 12 mi away
  • Alliance Cancer Specialists, PC, Horsham · 16 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07392892

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

RecruitingPhase 1
  • Sidney Kimmel Comprehensive Cancer Center Thomas Jefferson University, Philadelphia
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

Recruiting
  • University of Pennsylania, Perelman School of Medicine, Philadelphia
Ages 18 to 89 · All sexes · Updated Sep 11, 2026 · NCT05753748

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

RecruitingPhase 1
  • Normunity Investigational Site, Philadelphia
  • Normunity Investigational Site, Philadelphia
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07182149

Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma

RecruitingPhase 2
  • Abramson Cancer Center of the University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT06340711

Esophageal Adenocarcinoma trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.