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Head and Neck Squamous Cell Carcinoma clinical trials in Orange, CA

8 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Orange (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

RecruitingPhase 2
  • UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06980038

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

RecruitingPhase 2
  • UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange
Ages 18 to 79 · All sexes · Updated Sep 22, 2026 · NCT04671667

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • University of California Irvine Medical Center, Orange
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

RecruitingPhase 2
  • UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

RecruitingPhase 1
  • UC Irvine Health - Chao Family Comprehensive Cancer Center, Orange
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05208762

A Study of VET3-TGI in Patients With Solid Tumors

RecruitingPhase 1
  • UC Irvine Health, Orange
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT06444815

Single-Center Eval of Clinical & Radiological Benefit AHCC in Combo W/ SOC Tx for HPV+ Pts W/ HNSCC

RecruitingPhase 2
  • Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange
Ages 18 to 79 · All sexes · Updated Mar 27, 2025 · NCT06693323

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Orange

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.