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Down Syndrome clinical trials in Knoxville, TN

3 studies for Down Syndrome are looking for participants at sites in and around Knoxville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

RecruitingPhase 2
  • East Tennessee Childrens Hospital, Knoxville
Ages 1 to 30 · All sexes · Updated Sep 1, 2026 · NCT04546399

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

RecruitingObservational study
  • East Tennessee Childrens Hospital, Knoxville
Ages 6 to 39 · All sexes · Updated Aug 25, 2026 · NCT05702645

Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome

RecruitingPhase 3
  • Woolfson Eye Institute, Knoxville
Ages 8 and older · All sexes · Updated Feb 2, 2026 · NCT07135167

About Down Syndrome

About 1 in 700 babies are born with the birth defect known as Down Syndrome. Learn about the different Down Syndrome types and related health issues.

More about Down Syndrome on MedlinePlus

Down Syndrome trials in other cities

Other studies in Knoxville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.