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Down Syndrome clinical trials in Cleveland, OH

5 studies for Down Syndrome are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Down Syndrome Obstructive Sleep Apnea

RecruitingPhase 2
  • Rainbow Babies and Children's Hospital, Case Medical Center, Cleveland
Ages 5 to 18 · All sexes · Updated Sep 30, 2026 · NCT06043440

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

RecruitingPhase 2
  • Rainbow Babies and Childrens Hospital, Cleveland
Ages 1 to 30 · All sexes · Updated Sep 1, 2026 · NCT04546399

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

RecruitingObservational study
  • Rainbow Babies and Childrens Hospital, Cleveland
  • Cleveland Clinic Foundation, Cleveland
Ages 6 to 39 · All sexes · Updated Aug 25, 2026 · NCT05702645

Trial-Ready Cohort-Down Syndrome (TRC-DS)

RecruitingObservational study
  • Case Western Reserve University, Beachwood · 10 mi away
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109

Pediatric Down Syndrome Post-Approval Study

Recruiting
  • Cleveland Clinic Foundation, Cleveland
Ages 13 to 18 · All sexes · Updated Feb 28, 2025 · NCT06851338

About Down Syndrome

About 1 in 700 babies are born with the birth defect known as Down Syndrome. Learn about the different Down Syndrome types and related health issues.

More about Down Syndrome on MedlinePlus

Down Syndrome trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.