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Down Syndrome clinical trials in Philadelphia, PA

5 studies for Down Syndrome are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

Down Syndrome Obstructive Sleep Apnea

RecruitingPhase 2
  • Children's Hospital of Philadelphia, Philadelphia
Ages 5 to 18 · All sexes · Updated Sep 30, 2026 · NCT06043440

Endotype DIrected Treatment for OSA in Down Syndrome

RecruitingPhase 4
  • Children's Hospital of Philadelphia, Philadelphia
Ages 6 and older · All sexes · Updated Sep 3, 2026 · NCT07280468

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

RecruitingPhase 2
  • Children's Hospital of Philadelphia, Philadelphia
  • Saint Christopher's Hospital for Children, Philadelphia
  • Alfred I duPont Hospital for Children, Wilmington · 25 mi away
Ages 1 to 30 · All sexes · Updated Sep 1, 2026 · NCT04546399

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

RecruitingObservational study
  • Children's Hospital of Philadelphia, Philadelphia
  • Alfred I duPont Hospital for Children, Wilmington · 25 mi away
Ages 6 to 39 · All sexes · Updated Aug 25, 2026 · NCT05702645

Collaboration for Down Syndrome Progress (CDP)

RecruitingObservational study
  • The Children's Hospital of Philadelphia, Philadelphia
  • The Children's Hospital of Philadelphia, Philadelphia
All ages · All sexes · Updated Jun 4, 2026 · NCT07625579

About Down Syndrome

About 1 in 700 babies are born with the birth defect known as Down Syndrome. Learn about the different Down Syndrome types and related health issues.

More about Down Syndrome on MedlinePlus

Down Syndrome trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.