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Down Syndrome clinical trials in Orlando, FL

5 studies for Down Syndrome are looking for participants at sites in and around Orlando (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)

RecruitingPhase 2
  • Clinical Study Site, Maitland · 6 mi away
Ages 40 to 55 · All sexes · Updated Sep 4, 2026 · NCT07636811

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

RecruitingPhase 2
  • AdventHealth Orlando, Orlando
  • Arnold Palmer Hospital for Children, Orlando
  • Nemours Children's Hospital, Orlando
Ages 1 to 30 · All sexes · Updated Sep 1, 2026 · NCT04546399

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

RecruitingObservational study
  • Nemours Children's Hospital, Orlando
Ages 6 to 39 · All sexes · Updated Aug 25, 2026 · NCT05702645

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

RecruitingPhase 1/2
  • Charter Research, LLC, Orlando
  • Headlands Horizons LLC, Orlando
Ages 35 to 85 · All sexes · Updated Jul 10, 2026 · NCT05462106

Measuring Aided Language Development

Recruiting
  • University of Central Florida - Innovative Center, Orlando
42 Months – 60 Months · All sexes · Updated May 16, 2025 · NCT06512168

About Down Syndrome

About 1 in 700 babies are born with the birth defect known as Down Syndrome. Learn about the different Down Syndrome types and related health issues.

More about Down Syndrome on MedlinePlus

Down Syndrome trials in other cities

Other studies in Orlando

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.