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Parkinson's Disease clinical trials in Boston, MA

19 studies for Parkinson's Disease are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

RecruitingPhase 2
  • Beth Israel Deaconess Medical Center, Boston
Ages 40 to 80 · All sexes · Updated Oct 2, 2026 · NCT06680830

A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease

RecruitingPhase 2/3
  • Site-071, Boston
Ages 40 to 80 · All sexes · Updated Sep 28, 2026 · NCT06976268

GBPDC: Gut-Brain in PD Consortium Master Protocol

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 21 to 80 · All sexes · Updated Sep 25, 2026 · NCT07567794

Low-dose Carbon Monoxide (HBI-002) Trial to Evaluate Safety, Tolerability, PK, and Biomarkers in Parkinson's Disease

RecruitingPhase 2
  • Massachusetts General Hospital, Boston
Ages 40 to 80 · All sexes · Updated Sep 21, 2026 · NCT07005180

A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

RecruitingPhase 2
  • Beth Israel Deaconess Medical Center (Site #211), Boston
Ages 30 to 80 · All sexes · Updated Sep 10, 2026 · NCT07432958

Parkinson's Foundation PD GENEration Genetic Registry

RecruitingObservational study
  • Massachusetts General Hospital (MGH), Boston
  • Beth Israel Deaconess Medical Center (BIDMC), Boston
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT04994015

A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications

RecruitingObservational study
  • Boston Medical Center, Boston
Ages 45 to 75 · All sexes · Updated Sep 4, 2026 · NCT07330258

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

RecruitingPhase 3
  • Massachusetts General Hospital, Boston
Ages 50 to 85 · All sexes · Updated Sep 3, 2026 · NCT07174310

A Novel Digital Music-based Autonomous Personalized Walking Intervention to Improve Gait and Walking Automaticity in Parkinson Disease

Recruiting
  • Boston University Center for Neurorehabilitation, Boston
Ages 40 and older · All sexes · Updated Aug 24, 2026 · NCT07705373

A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

RecruitingPhase 3
  • Tufts Medical Center - Neurology, Boston
  • Beth Israel Deaconess Medical Center, Boston
Ages 45 to 75 · All sexes · Updated Aug 4, 2026 · NCT06944522

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Boston University, Boston
  • Massachusetts General Hospital, Boston
Ages 30 and older · All sexes · Updated Jul 27, 2026 · NCT04477785

Natural History Study of Synucleinopathies

RecruitingObservational study
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT01799915

Dance and Energy Expenditure Among Adults With Parkinson's

RecruitingHealthy volunteers welcome
  • Northeastern University, Boston
Ages 18 to 85 · All sexes · Updated Apr 13, 2026 · NCT06425731

Cortical-Basal Ganglia Speech Networks

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Mar 25, 2026 · NCT04286308

Treating Parkinson's Disease Through Transplantation of Autologous Stem Cell-Derived Dopaminergic Neurons

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
Ages 45 to 80 · All sexes · Updated Mar 25, 2026 · NCT06687837

Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients

Recruiting
  • Boston University, Boston
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Mar 9, 2026 · NCT07455760

PET Imaging Evaluation of [11C]SY08

RecruitingEarly phase 1Healthy volunteers welcome
  • MGH, Charlestown · 1 mi away
Ages 50 to 80 · All sexes · Updated Dec 24, 2025 · NCT06098612

Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

RecruitingHealthy volunteers welcome
  • Massachusetts Eye and Ear Infirmary, Boston
All ages · All sexes · Updated Dec 2, 2025 · NCT05317390

Robotic Apparel to Prevent Freezing of Gait in Parkinson Disease

Recruiting
  • Boston University Sargent College of Health and Rehabilitation Sciences, Boston
Ages 18 to 90 · All sexes · Updated Jul 18, 2025 · NCT06602544

About Parkinson's Disease

Parkinson's disease (PD) is a movement disorder. It causes tremors, stiffness, and slow movement. It gets worse over time. Learn what can help.

More about Parkinson's Disease on MedlinePlus

Parkinson's Disease trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.