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Depression clinical trials in Florida

45 studies for Depression are looking for participants at sites in Florida.

Cities in Florida

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

  • Clinical Neuroscience Solutions Inc. - Jacksonville, Jacksonville
  • K2 Medical Research - Maitland, Maitland
  • Central Miami Medical Institute Llc., Miami
  • and 3 more
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07621237

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

  • CNS Healthcare, Jacksonville
  • Accel Research Sites - Maitland, Maitland
  • Aqualane Clinical Research, Naples
  • and 1 more
RecruitingPhase 3
Ages 18 to 85 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT06793397

The WeACT Program for Family Caregivers of People Living With Dementia

  • University of South Florida, Tampa
Recruiting
Ages 18 and older ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07342569

Unified Protocol: Community Connections

  • Child and Adolescent Mood and Anxiety Treatment Program, Coral Gables
Recruiting
Ages 7 to 17 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT06038721

A Remotely Delivered Tai Chi/Qigong Intervention for Older People Living With HIV

  • Florida International University, Miami
Recruiting
Ages 50 to 75 ยท All sexes ยท Updated Sep 16, 2026 ยท NCT06586619

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

  • University of South Florida, Department of Psychiatry and Behavioral Neuroscience, Tampa
RecruitingPhase 2
Ages 18 to 80 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07002034

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

  • Seaport Investigator Site, Jacksonville
  • Seaport Investigator Site, Lauderhill
  • Seaport Investigator Site, Orlando
  • and 2 more
RecruitingPhase 2
Ages 18 to 65 ยท All sexes ยท Updated Sep 14, 2026 ยท NCT07065240

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

  • Gulfcoast Clinical Research Center, Fort Myers
  • Sarkis Clinical Trials, Gainesville
  • Equipath Health and Research Tampa Bay, Llc, Riverview
RecruitingPhase 3
Ages 18 to 74 ยท All sexes ยท Updated Sep 8, 2026 ยท NCT07076407

A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

  • Draig Clinical Site, Hialeah
  • Draig Clinical Site, Orlando
  • Draig Clinical Site, Orlando
  • and 2 more
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Sep 2, 2026 ยท NCT07610473

Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients

  • Mayo Clinic, Jacksonville
RecruitingPhase 2
Ages 18 to 99 ยท All sexes ยท Updated Sep 2, 2026 ยท NCT07639359

A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression

  • Draig Clinical Site, Miami
  • Draig Clinical Site, New Port Richey
  • Draig Clinical Site, Orlando
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Aug 26, 2026 ยท NCT07300969

Mental Health in Primary Care

  • Mailman for Child Devlopment, Miami
  • Pediatric Mobile Clinic, Miami
  • UM Pediatric Mobile Clinic, Miami
  • and 3 more
RecruitingHealthy volunteers welcome
Ages 12 to 16 ยท All sexes ยท Updated Aug 18, 2026 ยท NCT05426057

NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

  • Neurocrine Clinical Site, Hollywood
  • Neurocrine Clinical Site, Tampa
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 11, 2026 ยท NCT06911112

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

  • Neurocrine Clinical Site, Maitland
  • Neurocrine Clinical Site, Miami
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 10, 2026 ยท NCT06963021

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

  • Encore Medical Research, Hollywood
  • K2 Medical Research - Maitland, Maitland
  • Life Medical Research Group Corp, Miami Gardens
  • and 5 more
RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Aug 6, 2026 ยท NCT07412756

E-Mindfulness Approaches for Living After Breast Cancer

  • Halifax Health Cancer Center for Hope - Daytona Beach, Daytona Beach
  • UF Health Cancer Institute - Gainesville, Gainesville
  • Mayo Clinic in Florida, Jacksonville
  • and 1 more
RecruitingPhase 3
Ages 18 to 50 ยท All sexes ยท Updated Aug 4, 2026 ยท NCT06748222

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

  • CNS Clinical Research Group, Coral Springs
  • Clinical Neuroscience Solutions, Inc., Jacksonville
  • Accel Research Sites Lakeland, Lakeland
  • and 4 more
RecruitingPhase 3
Ages 18 to 74 ยท All sexes ยท Updated Aug 3, 2026 ยท NCT06775379

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

  • D&H Doral Research Center-Doral /ID# 255458, Doral
  • Florida Research Center, Inc. /ID# 240775, Miami
  • Medical Research Group of Central Florida /ID# 256757, Orange City
  • and 2 more
RecruitingPhase 3
Ages 10 to 17 ยท All sexes ยท Updated Jul 27, 2026 ยท NCT04777357

Adapting Single Sessions Interventions for Type 1 Diabetes

  • Nemours Children's Hospital - FL, Orlando
Recruiting
Ages 12 to 17 ยท All sexes ยท Updated Jul 24, 2026 ยท NCT06752369

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

  • Neurocrine Clinical Site, Hollywood
  • Neurocrine Clinical Site, Maitland
  • Neurocrine Clinical Site, Maitland
  • and 5 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Jul 24, 2026 ยท NCT06966401

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

  • Intrepid Spirit Center - Eglin Air Force Base, Eglin Air Force Base
  • Naval School Explosive Ordance Disposal - Eglin Air Force Base, Eglin Air Force Base
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 13, 2026 ยท NCT05663034

TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

  • Joe DiMaggio, Hollywood
  • Nemours Foundation, Orlando
RecruitingObservational study
18 Months โ€“ 11 Years ยท All sexes ยท Updated Jul 6, 2026 ยท NCT07048574

The Neural Underpinnings of Depression and Cannabis Use in Young People Living With HIV

  • University of Miami, Miami
Recruiting
Ages 18 to 59 ยท All sexes ยท Updated Jun 29, 2026 ยท NCT05453513

ACT Together: Implementing a Web-Based Program With Brief Coaching for Parents of Children With Disabilities in Pediatric Outpatient Clinics

  • University of South Florida, Tampa
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jun 23, 2026 ยท NCT07360600

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapyยฎ System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

  • Mindful Behavioral Health, Boca Raton
  • Galiz Research LLC, Hialeah
  • Flourish Research - St. Augustine, Jacksonville
  • and 5 more
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jun 15, 2026 ยท NCT03887715

Clinical Trial on Agitation in Alzheimer's Dementia

  • ClinCloud, LLC, Melbourne
  • Central Miami Medical Institute, Miami
  • Visionary Investigators Network, Miami
  • and 4 more
RecruitingPhase 2
Ages 60 and older ยท All sexes ยท Updated May 20, 2026 ยท NCT05543681

Youth Emotional and Behavioral Treatment Study

  • Florida State University, Tallahassee
Recruiting
Ages 4 to 17 ยท All sexes ยท Updated May 14, 2026 ยท NCT07296939

Families With Pride ("Familias Con Orgullo").

  • University of Miami, Coral Gables
Recruiting
Ages 13 to 19 ยท All sexes ยท Updated May 13, 2026 ยท NCT06057337

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

  • CenExel, Hollywood
  • Bioresearch Partner, Miami
  • University of South Florida, Psychiatry and Behavioral Neurosciences, Tampa
RecruitingPhase 2
Ages 18 to 65 ยท All sexes ยท Updated May 11, 2026 ยท NCT06524830

Geolocation Positional System (GPS) Experience

  • University of Miami, Coral Gables
RecruitingHealthy volunteers welcome
Ages 18 to 50 ยท All sexes ยท Updated May 5, 2026 ยท NCT05991713

Neural and Psychiatric Consequences of Cannabis Use in Adolescents

  • University of Miami Clinical Research Building, Miami
RecruitingHealthy volunteers welcome
Ages 14 to 20 ยท All sexes ยท Updated Apr 22, 2026 ยท NCT06941298

Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment

  • Mayo Clinic in Florida, Jacksonville
Recruiting
Ages 18 to 90 ยท All sexes ยท Updated Apr 2, 2026 ยท NCT07221409

MBM and taVNS for Low Back Pain and Depressive Symptoms

  • Florida State University, Tallahassee
Recruiting
Ages 50 to 85 ยท All sexes ยท Updated Mar 25, 2026 ยท NCT07415941

Project HOPEFUL: A PN-RCT With Implementation Science

  • University of Florida, Gainesville
RecruitingHealthy volunteers welcome
Ages 55 and older ยท All sexes ยท Updated Mar 16, 2026 ยท NCT07475039

BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and Postmenopausal Women

  • Luxury Psychiatry Clinic, Winter Garden
Recruiting
Ages 40 and older ยท Women ยท Updated Feb 17, 2026 ยท NCT07413705

Potential Benefits of Parent Child Interaction Therapy (PCIT)

  • UF Health Child Psychiatry, Gainesville
  • UF Health Psychiatry San Jose, Jacksonville
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 89 ยท All sexes ยท Updated Feb 12, 2026 ยท NCT06827951

Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)

  • University of Miami Neuroimaging Facility, Coral Gables
  • Care Resource - Midtown Miami, Miami
Recruiting
Ages 18 and older ยท All sexes ยท Updated Feb 6, 2026 ยท NCT05136703

The Student Wellness and Emotional Growth Resiliency (SWAG-R) Program

  • Nova Southeastern University, Fort Lauderdale
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Dec 12, 2025 ยท NCT06652503

Supporting Health in Veterans With Heart Failure

  • VA Clinic - Gainesville, Gainesville
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Nov 13, 2025 ยท NCT05839067

Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

  • Neurocrine Clinical Site, Hollywood
  • Neurocrine Clinical Site, Maitland
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 29, 2025 ยท NCT06786624

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.