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Depression clinical trials in Orlando, FL
15 studies for Depression are looking for participants at sites in and around Orlando (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
RecruitingPhase 3
- Accel Research Sites - Maitland, Maitland · 6 mi away
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
RecruitingPhase 2
- Seaport Investigator Site, Orlando
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
Recruiting
- APG Research, LLC, Orlando
- Nova Psychiatry Inc., Orlando
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
RecruitingPhase 3
- Charter Research - Orlando, Orlando
- K2 Medical Research - Maitland, Maitland · 6 mi away
TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age
RecruitingObservational study
- Nemours Foundation, Orlando
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
RecruitingPhase 3
- Neurocrine Clinical Site, Maitland · 6 mi away
- Neurocrine Clinical Site, Maitland · 6 mi away
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
RecruitingPhase 2
- Clinical Research Site, Orlando
- Clinical Research Site, Maitland · 6 mi away
A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression
RecruitingPhase 2
- Draig Clinical Site, Orlando
- Draig Clinical Site, Orlando
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
RecruitingPhase 2
- Draig Clinical Site, Orlando
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
RecruitingPhase 3
- Neurocrine Clinical Site, Maitland · 6 mi away
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
RecruitingPhase 3
- Nova Psychiatry Inc. /ID# 270892, Orlando
Adapting Single Sessions Interventions for Type 1 Diabetes
Recruiting
- Nemours Children's Hospital - FL, Orlando
Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
RecruitingPhase 3
- Neurocrine Clinical Site, Maitland · 6 mi away
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
RecruitingPhase 4
- Clinical Research Site, Orlando
- Clinical Research Site, Orlando
- Clinical Research Site, Orlando
The Lake Nona Life Project
RecruitingObservational studyHealthy volunteers welcome
- Lake Nona Institute, Orlando
About Depression
Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.
More about Depression on MedlinePlus
Depression trials in other cities
- Boston, MA50 studies
- New York City, NY44 studies
- Chicago, IL26 studies
- Atlanta, GA22 studies
- Pittsburgh, PA22 studies
- Philadelphia, PA21 studies
- Charleston, SC18 studies
- San Diego, CA18 studies
- Houston, TX18 studies
- Los Angeles, CA17 studies
- Washington, DC16 studies
- San Francisco, CA15 studies
Other studies in Orlando
- Non-Small Cell Lung Cancer47 studies
- Obesity33 studies
- Alzheimer's Disease29 studies
- Metastatic Cancer28 studies
- Overweight27 studies
- Type 2 Diabetes25 studies
- Ovarian Cancer24 studies
- Cancer (all types)24 studies
- Breast Cancer23 studies
- Lung Cancer23 studies
- Ulcerative Colitis21 studies
- Colorectal Cancer21 studies
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.