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Depression clinical trials in Tampa, FL

11 studies for Depression are looking for participants at sites in and around Tampa (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

RecruitingPhase 3
  • K2 Medical Research Tampa, Tampa
Ages 18 to 85 · All sexes · Updated Nov 13, 2026 · NCT06793397

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

RecruitingPhase 2
  • University of South Florida, Department of Psychiatry and Behavioral Neuroscience, Tampa
Ages 18 to 80 · All sexes · Updated Nov 10, 2026 · NCT07002034

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

RecruitingPhase 3
  • K2 Medical Research - Tampa, Tampa
Ages 18 to 75 · All sexes · Updated Nov 4, 2026 · NCT07412756

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Tampa
  • Neurocrine Clinical Site, Tampa
  • Neurocrine Clinical Site, Tampa
Ages 18 and older · All sexes · Updated Nov 2, 2026 · NCT06966401

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 2
  • Clinical Research Site, Tampa
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT07621237

The WeACT Program for Family Caregivers of People Living With Dementia

Recruiting
  • University of South Florida, Tampa
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT07342569

A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

RecruitingPhase 2
  • Draig Clinical Site, Tampa
  • Draig Clinical Site, Tampa
Ages 18 to 75 · All sexes · Updated Oct 14, 2026 · NCT07610473

NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Tampa
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06911112

ACT Together: Implementing a Web-Based Program With Brief Coaching for Parents of Children With Disabilities in Pediatric Outpatient Clinics

Recruiting
  • University of South Florida, Tampa
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT07360600

Cocooned Moms Study

Recruiting
  • Dr.Traci's House, Tampa
Ages 18 and older · Women · Updated Jun 15, 2025 · NCT06968650

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Tampa

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.