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Depression clinical trials in Miami, FL

16 studies for Depression are looking for participants at sites in and around Miami (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 2
  • Central Miami Medical Institute Llc., Miami
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07621237

A Remotely Delivered Tai Chi/Qigong Intervention for Older People Living With HIV

Recruiting
  • Florida International University, Miami
Ages 50 to 75 · All sexes · Updated Sep 16, 2026 · NCT06586619

A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression

RecruitingPhase 2
  • Draig Clinical Site, Miami
Ages 18 to 75 · All sexes · Updated Aug 26, 2026 · NCT07300969

Mental Health in Primary Care

RecruitingHealthy volunteers welcome
  • Mailman for Child Devlopment, Miami
  • Pediatric Mobile Clinic, Miami
  • UM Pediatric Mobile Clinic, Miami
  • and 3 more
Ages 12 to 16 · All sexes · Updated Aug 18, 2026 · NCT05426057

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Miami
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06963021

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

RecruitingPhase 3
  • PharmaSouth Research, Miami
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Miami
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06966401

The Neural Underpinnings of Depression and Cannabis Use in Young People Living With HIV

Recruiting
  • University of Miami, Miami
Ages 18 to 59 · All sexes · Updated Jun 29, 2026 · NCT05453513

Clinical Trial on Agitation in Alzheimer's Dementia

RecruitingPhase 2
  • Central Miami Medical Institute, Miami
  • Visionary Investigators Network, Miami
  • Miami Jewish Health, Miami
Ages 60 and older · All sexes · Updated May 20, 2026 · NCT05543681

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

RecruitingPhase 2
  • Bioresearch Partner, Miami
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830

Neural and Psychiatric Consequences of Cannabis Use in Adolescents

RecruitingHealthy volunteers welcome
  • University of Miami Clinical Research Building, Miami
Ages 14 to 20 · All sexes · Updated Apr 22, 2026 · NCT06941298

Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)

Recruiting
  • Care Resource - Midtown Miami, Miami
Ages 18 and older · All sexes · Updated Feb 6, 2026 · NCT05136703

Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study

RecruitingObservational studyHealthy volunteers welcome
  • Miami-Dade County Parks, Recreation and Open Spaces Department, Miami
Ages 6 to 14 · All sexes · Updated Sep 4, 2025 · NCT06595251

Cocooned Moms Study

Recruiting
  • University Of Miami, Miami
Ages 18 and older · Women · Updated Jun 15, 2025 · NCT06968650

A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

RecruitingPhase 4
  • Clinical Research Site, Miami
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Miami

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.