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Depression clinical trials in Texas

51 studies for Depression are looking for participants at sites in Texas.

Cities in Texas

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

  • Austin Clinical Trial Partners, Austin
  • FutureSearch Trials of Dallas, Dallas
  • Revival Research Institute, Llc - McKinney, Tx, McKinney
  • and 1 more
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Sep 25, 2026 ยท NCT07621237

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

  • Adams Clinical Dallas, DeSoto
  • Brain Health Consultants and TMS Center, Houston
  • Flourish Research San Antonio, San Antonio
RecruitingPhase 3
Ages 18 to 85 ยท All sexes ยท Updated Sep 25, 2026 ยท NCT06793397

Parent-Adolescent Relationships, Emotional Regulation, and HRV in Adolescents With Depression

  • Child and adolescent psychiatrist at the Children's Health Psychiatry Clinic., Dallas
RecruitingObservational study
Ages 12 to 18 ยท All sexes ยท Updated Sep 21, 2026 ยท NCT07430774

Brexanolone Lifting Outcomes Of Moms

  • Lipocine Investigational Site, Plano
  • Lipocine Investigational Site, Richardson
RecruitingPhase 3
Ages 15 to 45 ยท Women ยท Updated Sep 16, 2026 ยท NCT07822321

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

  • Dell Medical School, University of Texas at Austin, Austin
RecruitingPhase 2
Ages 18 to 80 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT07002034

Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression

  • Wells Medicine, Houston
  • Texas A&M (Houston Methodist Hospital Location), Houston
RecruitingPhase 1Healthy volunteers welcome
Ages 21 to 45 ยท All sexes ยท Updated Sep 15, 2026 ยท NCT06480201

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

  • Seaport Investigator Site, Dallas
  • Seaport Investigator Site, Irving
  • Seaport Investigator Site, Richardson
RecruitingPhase 2
Ages 18 to 65 ยท All sexes ยท Updated Sep 14, 2026 ยท NCT07065240

Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children

  • Steven A. Cohen Military Family Clinic at Endeavors, El Paso, El Paso
  • Steven A. Cohen Military Family Clinic at Endeavors, Killeen, Killeen
  • Steven A. Cohen Military Family Clinic at Endeavors, San Antonio, San Antonio
Recruiting
Ages 18 and older ยท Women ยท Updated Sep 11, 2026 ยท NCT06262178

Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy

  • MD Anderson Cancer Center, Houston
RecruitingPhase 2
Ages 25 and older ยท All sexes ยท Updated Sep 11, 2026 ยท NCT06200155

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

  • Austin Clinical Trial Partners, Austin
RecruitingPhase 3
Ages 18 to 74 ยท All sexes ยท Updated Sep 8, 2026 ยท NCT07076407

PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study

  • Houston Center for Advanced Psychiatric Treatment, Bellaire
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 8, 2026 ยท NCT06713616

MH-POWER for College Students on the Spectrum

  • Department of Occupational Therapy, ESWOT Building, University of Texas Rio Grande Valley, Edinburg
Recruiting
Ages 18 to 30 ยท All sexes ยท Updated Sep 3, 2026 ยท NCT07682753

A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

  • Draig Clinical Site, DeSoto
  • Draig Clinical Site, Fort Worth
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Sep 2, 2026 ยท NCT07610473

Neurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story

  • Texas Children's Hospital, Houston
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Aug 31, 2026 ยท NCT05809115

A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression

  • Draig Clinical Site, Austin
  • Draig Clinical Site, Austin
  • Draig Clinical Site, DeSoto
  • and 2 more
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Aug 26, 2026 ยท NCT07300969

Accelerated rTMS for Substance Use Disorder and Depression

  • UT Southwestern Medical Center, Dallas
Recruiting
Ages 18 to 65 ยท All sexes ยท Updated Aug 24, 2026 ยท NCT06424184

Accelerated Intermittent Theta Burst in Treatment-Naive Adolescents

  • Dell Medical School at University of Texas at Austin, Austin
Recruiting
Ages 13 to 20 ยท All sexes ยท Updated Aug 19, 2026 ยท NCT06523439

Cognitive Training as an Adjunct to Ketamine in Real-world Clinics

  • Baylor College of Medicine, Houston
Recruiting
Ages 18 to 80 ยท All sexes ยท Updated Aug 19, 2026 ยท NCT06526078

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

  • The University of Texas M. D. Anderson Cancer Center, Houston
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Aug 12, 2026 ยท NCT06801041

NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

  • Neurocrine Clinical Site, DeSoto
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 11, 2026 ยท NCT06911112

A Computerized Depression Intervention in Veterans

  • Central Texas Veterans Health Care System Waco VA Medical Center, Waco, TX, Waco
Recruiting
Ages 18 and older ยท All sexes ยท Updated Aug 10, 2026 ยท NCT06217198

A Study of Brenipatide in Adult Participants With Major Depressive Disorder

  • Adams Clinical Dallas, DeSoto
  • Re:Cognition Health - Fort Worth, Fort Worth
  • Consano Clinical Research, LLC, Shavano Park
RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Aug 6, 2026 ยท NCT07412756

Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia

  • The University of Texas Health Science Center at Houston, Houston
Recruiting
Ages 18 to 60 ยท All sexes ยท Updated Aug 5, 2026 ยท NCT07060066

Telehealth Behavioral Activation for Teens

  • Baylor College of Medicine, Houston
Recruiting
Ages 12 to 18 ยท All sexes ยท Updated Aug 4, 2026 ยท NCT06273995

E-Mindfulness Approaches for Living After Breast Cancer

  • The Don and Sybil Harrington Cancer Center, Amarillo
RecruitingPhase 3
Ages 18 to 50 ยท All sexes ยท Updated Aug 4, 2026 ยท NCT06748222

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

  • Delricht Research - Plano, Plano
  • Aim Trials, Llc, Plano
  • Grayline Research Center, Wichita Falls
RecruitingPhase 3
Ages 18 to 74 ยท All sexes ยท Updated Aug 3, 2026 ยท NCT06775379

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

  • Beaumont Psychiatric Clinic /ID# 267484, Beaumont
  • Houston Clinical Trials - Bellaire /ID# 274189, Bellaire
  • Texas Research Group /ID# 270050, Coppell
  • and 7 more
RecruitingPhase 3
Ages 10 to 17 ยท All sexes ยท Updated Jul 27, 2026 ยท NCT04777357

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

  • Neurocrine Clinical Site, Bellaire
  • Neurocrine Clinical Site, Dallas
  • Neurocrine Clinical Site, DeSoto
  • and 3 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Jul 24, 2026 ยท NCT06966401

Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)

  • Parkland Health & Hospital System, Dallas
RecruitingHealthy volunteers welcome
All ages ยท All sexes ยท Updated Jul 9, 2026 ยท NCT03906435

TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

  • UT Southwestern, Plano
RecruitingObservational study
18 Months โ€“ 11 Years ยท All sexes ยท Updated Jul 6, 2026 ยท NCT07048574

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapyยฎ System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

  • UT Health Austin, Mulva Clinic for the Neurosciences, Austin
  • University of Texas Southwestern, Dallas
  • Texas Tech University Health Science Center, El Paso
  • and 2 more
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jun 15, 2026 ยท NCT03887715

Cancer Pain Management Using a Web-based Intervention

  • The University of Texas at Austin, Austin
Recruiting
Ages 18 and older ยท Women ยท Updated Jun 9, 2026 ยท NCT06085313

Exploring Virtual Reality Adventure Training Exergaming

  • University of Texas at Arlington, Arlington
RecruitingHealthy volunteers welcome
Ages 18 to 45 ยท Women ยท Updated Jun 1, 2026 ยท NCT05563805

Effects of Exercise and Virtual Reality on Depression

  • UTArlington, Arlington
RecruitingHealthy volunteers welcome
Ages 18 to 65 ยท All sexes ยท Updated May 29, 2026 ยท NCT05973461

Clinical Trial on Agitation in Alzheimer's Dementia

  • Senior Adults Specialty Research, Austin
  • Baylor Scott and White Research Institute, Dallas
  • Kerwin Medical Center, Dallas
RecruitingPhase 2
Ages 60 and older ยท All sexes ยท Updated May 20, 2026 ยท NCT05543681

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

  • Biobehavioral Research of Austin, Austin
  • InSite Clinical Research, DeSoto
  • Aim Trials, LLC, Plano
RecruitingPhase 2
Ages 18 to 65 ยท All sexes ยท Updated May 11, 2026 ยท NCT06524830

Transcutaneous Vagus Nerve Stimulation for Attention and Memory

  • Michael E. DeBakey VA Medical Center, Houston
  • Michael E. DeBakey VA Medical Center, Houston
Recruiting
Ages 25 to 64 ยท All sexes ยท Updated May 7, 2026 ยท NCT06723743

Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia

  • Houston Center For Advanced Psychiatric Treatment, Houston
Recruiting
Ages 22 to 75 ยท All sexes ยท Updated May 1, 2026 ยท NCT06982820

Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression

  • Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600, Austin
RecruitingPhase 4
Ages 18 to 65 ยท All sexes ยท Updated May 1, 2026 ยท NCT05892744

rTMS for Military TBI-related Depression

  • William Beaumont Army Medical Center, Fort Bliss
Recruiting
Ages 18 to 55 ยท All sexes ยท Updated Apr 29, 2026 ยท NCT05426967

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.