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Depression clinical trials in Plano, TX

6 studies for Depression are looking for participants at sites in and around Plano (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 2
  • Delricht Research - Plano, Plano
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07621237

Brexanolone Lifting Outcomes Of Moms

RecruitingPhase 3
  • Lipocine Investigational Site, Plano
Ages 15 to 45 · Women · Updated Sep 16, 2026 · NCT07822321

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

RecruitingPhase 3
  • Delricht Research - Plano, Plano
  • Aim Trials, Llc, Plano
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379

TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

RecruitingObservational study
  • UT Southwestern, Plano
18 Months – 11 Years · All sexes · Updated Jul 6, 2026 · NCT07048574

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

RecruitingPhase 2
  • Aim Trials, LLC, Plano
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Plano

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.