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Depression clinical trials in Dallas, TX

13 studies for Depression are looking for participants at sites in and around Dallas (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 2
  • FutureSearch Trials of Dallas, Dallas
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07621237

Parent-Adolescent Relationships, Emotional Regulation, and HRV in Adolescents With Depression

RecruitingObservational study
  • Child and adolescent psychiatrist at the Children's Health Psychiatry Clinic., Dallas
Ages 12 to 18 · All sexes · Updated Sep 21, 2026 · NCT07430774

A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)

RecruitingPhase 2
  • Seaport Investigator Site, Dallas
Ages 18 to 65 · All sexes · Updated Sep 14, 2026 · NCT07065240

Accelerated rTMS for Substance Use Disorder and Depression

Recruiting
  • UT Southwestern Medical Center, Dallas
Ages 18 to 65 · All sexes · Updated Aug 24, 2026 · NCT06424184

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Dallas
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06966401

Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)

RecruitingHealthy volunteers welcome
  • Parkland Health & Hospital System, Dallas
All ages · All sexes · Updated Jul 9, 2026 · NCT03906435

Clinical Trial on Agitation in Alzheimer's Dementia

RecruitingPhase 2
  • Baylor Scott and White Research Institute, Dallas
  • Kerwin Medical Center, Dallas
Ages 60 and older · All sexes · Updated May 20, 2026 · NCT05543681

Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O)

Recruiting
  • UT Southwestern Parkland Health and Hospital System, Dallas
Ages 18 and older · Women · Updated Apr 3, 2026 · NCT05752448

Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

Recruiting
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 to 24 · All sexes · Updated Nov 6, 2025 · NCT05869552

Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Dallas
Ages 18 and older · All sexes · Updated Oct 29, 2025 · NCT06786624

A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

RecruitingPhase 4
  • Clinical Research Site, Dallas
  • Clinical Research Site, Dallas
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Dallas

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.