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Heart Diseases clinical trials in Durham, NC

10 studies for Heart Diseases are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

ELEVATE-HFpEF Clinical Study

Recruiting
  • Duke University Medical Center, Durham
Ages 40 and older · All sexes · Updated Oct 2, 2026 · NCT06678841

Personalized Environment and Genes Study

RecruitingObservational studyHealthy volunteers welcome
  • NIEHS Clinical Research Unit (CRU), Research Triangle Park · 7 mi away
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 to 120 · All sexes · Updated Sep 16, 2026 · NCT00341237

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • Duke University, Durham
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

RecruitingPhase 3
  • Duke University Medical Center, Durham
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • UNC Medical Center, Durham
  • Duke University, Durham
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Recruiting
  • Duke University, Durham
Ages 18 and older · Women · Updated Apr 1, 2026 · NCT04124120

PKP2-ACM Natural History Study

RecruitingObservational study
  • Duke University, Durham
Ages 12 and older · All sexes · Updated Feb 27, 2026 · NCT06644742

Sex Differences in Barriers and Participation in Physical Activity During and Following Cardiac Rehabilitation

RecruitingObservational study
  • Duke Center for Living, Durham
Ages 18 and older · All sexes · Updated Dec 3, 2025 · NCT07214350

Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)

RecruitingObservational study
  • Duke University Medical Center, Durham
0 Months – 20 Years · All sexes · Updated Nov 14, 2025 · NCT05055830

About Heart Diseases

Heart disease is the leading cause of death in the U.S. Learn about the different types of heart diseases, and what you can do to try to prevent them.

More about Heart Diseases on MedlinePlus

Heart Diseases trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.