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Heart Failure clinical trials in Illinois
44 studies for Heart Failure are looking for participants at sites in Illinois.
Cities in Illinois
- Chicago31 studies
- Naperville13 studies
- Evanston8 studies
- Peoria8 studies
- Arlington Heights7 studies
- Waukegan4 studies
- Cicero3 studies
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
- Northwest Heart Clinical Research, LLC, Arlington Heights
- Illinois Masonic Hospital, Chicago
- Chicago Medical Research, Hazel Crest
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06424288A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
- Northwest Heart Clinical Research, LLC, Arlington Heights
- Chicago Medical Research, Hazel Crest
- Clinical Investigation Specialists, Inc., Libertyville
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06935370HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
- Northwestern University, Chicago
RecruitingObservational studyHealthy volunteers welcome
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT05873634Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
- Northwestern University, Chicago
RecruitingObservational studyHealthy volunteers welcome
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT06517186A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
- Research Site, Chicago
- Research Site, Gurnee
- Research Site, Melrose Park
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
- Midwest Cardiovascular Institute, Naperville
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
- Chicago Medical Research LLC, Hazel Crest
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459Alleviant ALLAY-HFrEF Study
- Midwest Cardiovascular Institute, Naperville
Recruiting
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06812533Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Champaign
- Research Site, Chicago
- Research Site, Chicago
- and 4 more
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
- Research Site, Chicago
- Research Site, Hazel Crest
- Research Site, Peoria
- and 1 more
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Sep 11, 2026 · NCT06307652A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
- CON-10021, Glenview, IL, Glenview
- CON-10041, Island Lake, IL, Island Lake
- CON-10025, Naperville, IL, Naperville
- and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
- Chicago, IL Investigative Site 10062, Chicago
- Glenview, IL Investigative Site 10021, Glenview
- Naperville, IL Investigative Site 10025, Naperville
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
- Advocate Christ Medical Center, Chicago
- Northwestern University, Chicago
- University of Chicago, Chicago
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
- University of Chicago, Hinsdale
- Midwest Cardiovascular Institute, Naperville
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07069738A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
- Local Institution - 153, Peoria
RecruitingPhase 2
Ages 30 to 84 · All sexes · Updated Aug 31, 2026 · NCT07795814AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
- Methodist Medical Center of Illinois, Peoria
RecruitingPhase 2
Ages 40 to 85 · All sexes · Updated Aug 27, 2026 · NCT06793371Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
- Research Site, Chicago
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07690436Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
- University of Chicago, Chicago
- Advocate IMMC, Chicago
- Ascenscion Alexian Brothers, Elk Grove Village
Recruiting
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs
- Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
RecruitingObservational study
Up to age 18 · All sexes · Updated Aug 25, 2026 · NCT06532890A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
- University of Chicago Dept of Medicine, Chicago
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05489705LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
- Tenax Investigational Site, Chicago
- Tenax Investigational Site, Chicago
- Tenax Investigational Site, Mount Prospect
- and 1 more
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Aug 19, 2026 · NCT07288398A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
- Chicago Clinical Research Institute INC, Chicago
- Univer Of Illinois at Chicago, Chicago
- Eagle Clinical Research, Chicago
- and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001Alleviant ALLAY-HF Study
- Midwest Cardiovascular Institute, Naperville
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303Study of the Progression of Chronic Cardiovascular Conditions
- Prolaio, Chicago
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT07420907Cardiac Power Output in Cardiogenic Shock Patients
- The University of Chicago, Chicago
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05700617ELEVATE-HFpEF Clinical Study
- The University of Chicago Medical Center, Chicago
Recruiting
Ages 40 and older · All sexes · Updated Aug 3, 2026 · NCT06678841Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure
- Northwestern University, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT06526988A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
- FIN-10019, Peoria, IL, Peoria
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06033950PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- Advocate Health System, Downers Grove
- Heart Care Centers of Illinois (HCCI), Palos Park
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- University of Chicago, Chicago
- Advocate Health & Hospitals Corporation, Oakbrook Terrace
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
- NMH Clinical Research Unit, Chicago
- Northwestern Memorial HealthCare - Arkes Pavilion, Chicago
- Northwestern Memorial HealthCare - Feinberg Pavilion, Chicago
- and 4 more
RecruitingPhase 2
Ages 18 to 79 · All sexes · Updated May 27, 2026 · NCT06991257Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)
- University of Chicago, Chicago
RecruitingObservational study
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06641362The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
- Advocate Good Samaritan, Downers Grove
- Midwest Cardiovascular Institute (MCI), Naperville
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
- Northwestern University Feinberg School of Medicine, Chicago
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Mar 24, 2026 · NCT06217302XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
- Northwestern Memorial Hospital, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06895070Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)
- Northwestern University, Chicago
RecruitingObservational study
Ages 21 and older · All sexes · Updated Mar 18, 2026 · NCT07059962His-Bundle Corrective Pacing in Heart Failure
- Northwestern Memorial Hospital, Chicago
- Rush University Medical Center, Chicago
- University of Chicago, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Feb 9, 2026 · NCT05265520iCardia4HF: Multi-component mHealth Intervention for Patients With Heart Failure
- Rush University Medical Center, Chicago
- University of Illinois Hospital & Health Sciences System, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Jan 30, 2026 · NCT06205225Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
- University of Chicago, Chicago
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Dec 16, 2025 · NCT06039176Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure
- Endotronix, Naperville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 19, 2025 · NCT06783335From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.