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Heart Failure clinical trials in Minnesota
43 studies for Heart Failure are looking for participants at sites in Minnesota.
Cities in Minnesota
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
- Mayo Clinic, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT05873634Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
- Mayo Clinic, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT06517186Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)
- University of Minnesota, Minneota
Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07222813A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
- Minneapolis VA Health Care System, Minneapolis
- Mayo Clinic, Rochester, Rochester
- Regions Hospital, Saint Paul
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06935370A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
- Minneapolis VA Health Care System, Minneapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06424288Alleviant ALLAY-HFrEF Study
- Minneapolis Heart Institute Foundation, Minneapolis
Recruiting
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06812533Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
- Mankato Clinic, Mankato
- Fairview Health Services M Health Fairview St Johns Hospital, Maplewood
- University of Minnesota, Minneapolis
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Mankato
- Research Site, Minneapolis
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
- Research Site, Saint Paul
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Sep 11, 2026 · NCT06307652A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
- Minneapolis, MN Investigative Site 10091, Minneapolis
- Minneapolis, MN Investigative Site 10035, Minneapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
- Minneapolis, MN Investigative Site CON-10035, Minneapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
- Abbott Northwestern Hospital, Minneapolis
- University of Minnesota, Minneapolis
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
- St. Mary's Duluth Clinic Regional Heart Center, Duluth
- Centracare Heart and Vascular Center, Saint Cloud
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07069738AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
- Mayo Clinic, Rochester
RecruitingPhase 2
Ages 40 to 85 · All sexes · Updated Aug 27, 2026 · NCT06793371Rilonacept in Subjects With Cardiac Sarcoidosis
- Mayo Clinic in Rochester, Rochester
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Aug 20, 2026 · NCT06660732Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
- Coon Rapids
- Minneapolis
- Robbinsdale
- and 2 more
RecruitingObservational study
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume
- Mayo Clinic in Rochester, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT06195059LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
- Tenax Investigational Site, Minneapolis
- Tenax Investigational Site, Rochester
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Aug 19, 2026 · NCT07288398A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
- Minneapolis Heart Institute Foundation, Minneapolis
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05489705Alleviant ALLAY-HF Study
- Minneapolis Heart Institute Foundation, Minneapolis
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
- Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis
Recruiting
Ages 60 and older · All sexes · Updated Aug 14, 2026 · NCT05996328Inspiratory Muscle Training in HFpEF
- Mayo Clinic in Rochester, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06510231Assessment of CCM in HF With Higher Ejection Fraction
- Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis
Recruiting
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709ELEVATE-HFpEF Clinical Study
- M Health Fairview University of Minnesota Medical Center - East Bank, Minneapolis
Recruiting
Ages 40 and older · All sexes · Updated Aug 3, 2026 · NCT06678841Community-Informed Interventions for Equitable Congestive Heart Failure Management in Primary Care
- Mayo Clinic, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT07730827A Study to Evaluate Breathing Muscle Training in Cardiac Rehab
- Mayo Clinic in Rochester, Rochester
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 17, 2026 · NCT04984473A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
- Minneapolis, MN Investigative Site FIN-10035, Minneapolis
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06033950A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
- Mayo Clinic, Rochester
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Jun 30, 2026 · NCT07137338PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- University of Minnesota, Minneapolis
- Centra Care Heart Center, Saint Cloud
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Minneapolis Heart Institute, Minneapolis
- Mayo Clinic, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)
- Mayo Clinic, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06641362CCM OPEN HF Registry
- Minneapolis Heart Institute Research Foundation, Minneapolis
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT07112924A Study of Paramedic HF Management
- Mayo Clinic, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT06874556The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
- CentraCare Heart and Vascular, Saint Cloud
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
- Mayo Clinic, Rochester
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06271577AI-Guided Left Bundle Branch Area Pacing
- Mayo Clinic in Rochester, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07206602His Bundle Pacing in Bradycardia and Heart Failure
- Mayo Clinic, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 24, 2025 · NCT03008291Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance
- Minneapolis Heart Institute Foundation, Minneapolis
RecruitingObservational study
Ages 18 and older · All sexes · Updated Dec 23, 2025 · NCT07131631Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
- Mayo Clinic-Rochester, Rochester
RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Dec 16, 2025 · NCT06039176Left vs Left Randomized Clinical Trial
- Mayo Clinic, Rochester
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05650658From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.