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HIV clinical trials in Houston, TX

17 studies for HIV are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

RecruitingObservational study
  • UT Health, Houston
  • Thomas Street at Quentin Mease Health Center, Houston
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07473778

A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed

RecruitingPhase 3
  • GSK Investigational Site, Houston
Ages 12 and older · All sexes · Updated Sep 28, 2026 · NCT07650916

ADELANTE: A Randomized Controlled Trial to Improve Engagement in Care for Latinos With HIV

Recruiting
  • Baylor College of Medicine, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06274632

A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)

RecruitingPhase 2/3
  • Saint Hope Foundation, Inc. ( Site 1504), Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07266831

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

RecruitingPhase 1/2
  • 5128, Baylor College of Medicine/Texas Children's Hospital Clinical Research Site, Houston
48 Hours · All sexes · Updated Sep 9, 2026 · NCT02140255

Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
All ages · All sexes · Updated Sep 4, 2026 · NCT02479698

A Clinical Trial to Look at the Safety and Immune Responses of the RNA-based Vaccine BNT168 in Adults Living With or Without HIV

RecruitingPhase 1Healthy volunteers welcome
  • The Crofoot Research Center, Houston
Ages 18 to 50 · All sexes · Updated Aug 21, 2026 · NCT07698600

Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

Recruiting
  • University of Texas M.D. Anderson Cancer Center, Houston
Ages 45 to 80 · All sexes · Updated Aug 19, 2026 · NCT04949464

Positive Peers Intervention Clinical Trial

Recruiting
  • Thomas Street Clinic, Houston
Ages 13 to 34 · All sexes · Updated Aug 18, 2026 · NCT06388109

Screen2Prevent (S2P)

RecruitingHealthy volunteers welcome
  • Baylor College of Medicine, Houston
Ages 14 to 24 · All sexes · Updated Aug 17, 2026 · NCT07728123

A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV

RecruitingPhase 2
  • UT Health Houston, Houston
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07143968

A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

RecruitingPhase 2
  • GSK Investigational Site, Houston
  • GSK Investigational Site, Houston
  • GSK Investigational Site, Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT07202546

Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

Recruiting
  • Houston Methodist Research Institute, Houston
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT06263426

Menopausal HT for Women Living With HIV (HoT)

RecruitingPhase 4
  • Houston AIDS Research Team CRS (31473), Houston
Ages 40 to 60 · Women · Updated May 22, 2026 · NCT06856174

Assessing the Use of MY-RIDE, a Just-in-time Adaptive Intervention, to Improve HIV Prevention and Substance Use in Youth Experiencing Homelessness

Recruiting
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 to 25 · All sexes · Updated May 13, 2026 · NCT06074354

Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

RecruitingPhase 2
  • UT Health Houston, Houston
Ages 40 and older · All sexes · Updated Dec 17, 2025 · NCT05488431

Pharmacokinetics, Safety, Tolerability of Dolutegravir/Rilpivirine in Pediatrics

RecruitingPhase 1/2
  • GSK Investigational Site, Houston
  • GSK Investigational Site, Houston
Ages 6 to 12 · All sexes · Updated Sep 19, 2024 · NCT05674656

About HIV

HIV (human immunodeficiency virus) attacks the body’s immune system. There is no cure but it can be treated with medicines. To know if you have HIV, get tested.

More about HIV on MedlinePlus

HIV trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.