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HIV clinical trials in Boston, MA

11 studies for HIV are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital Vaccine CRS (BWH VCRS), Boston
Ages 18 to 60 · All sexes · Updated Sep 18, 2026 · NCT06665646

Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

RecruitingObservational study
  • Fenway Health, Boston
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07473778

Alcohol and "Heat of the Moment" Sexual Decision Making

RecruitingHealthy volunteers welcome
  • Boston University Department of Psychological and Brain Sciences, Boston
Ages 18 and older · Men · Updated Jul 20, 2026 · NCT05729256

Texting to Reduce Human Immunodeficiency Virus (HIV) Risk

Recruiting
  • South End Community Health Center, Boston
  • East Boston Neighborhood Health Center, Boston
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT06088277

Practice Facilitation as a Strategy to Improve Alcohol Treatment Adoption and Implementation in HIV Care

RecruitingHealthy volunteers welcome
  • Fenway Community Health, Boston
Ages 18 and older · All sexes · Updated Jun 26, 2026 · NCT05241990

Mitigating the Impact of Stigma and Shame Among People Living With HIV and Substance Use Disorders

Recruiting
  • Fenway Health, Boston
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT05934305

Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Jun 22, 2026 · NCT06263426

Menopausal HT for Women Living With HIV (HoT)

RecruitingPhase 4
  • 101 Massachusetts General Hospital (MGH) CRS, Boston
  • Brigham and Women's Hosp. ACTG CRS (107), Boston
Ages 40 to 60 · Women · Updated May 22, 2026 · NCT06856174

Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital Vaccine CRS (BWH VCRS), Boston
Ages 18 to 55 · All sexes · Updated Sep 25, 2025 · NCT06796686

Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 50 and older · All sexes · Updated Sep 22, 2025 · NCT06001814

A Mobile Gaming App to Improve Adherence to PrEP

RecruitingHealthy volunteers welcome
  • Boston Medical Center, Boston
Ages 15 to 34 · All sexes · Updated May 14, 2025 · NCT05762705

About HIV

HIV (human immunodeficiency virus) attacks the body’s immune system. There is no cure but it can be treated with medicines. To know if you have HIV, get tested.

More about HIV on MedlinePlus

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Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.