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Long COVID clinical trials in San Francisco, CA

8 studies for Long COVID are looking for participants at sites in and around San Francisco (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

RecruitingPhase 3
  • Optimus Medical ( Site 3817), San Francisco
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT06667700

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

RecruitingPhase 3
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06631287

A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses

RecruitingPhase 1/2Healthy volunteers welcome
  • UCSF Community and Clinical Research Center, San Francisco
Ages 40 to 64 · All sexes · Updated Aug 18, 2026 · NCT06810934

Validation of Biomarkers for Long COVID in the LIINC Viral Immunopathogenesis and Persistence Repeat Donor Cohort (VIPER)

RecruitingObservational studyHealthy volunteers welcome
  • Zuckerberg San Francisco General Hospital, San Francisco
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07770022

Long-term Impact of Infection With Novel Coronavirus (COVID-19)

RecruitingObservational study
  • Zuckerberg San Francisco General Hospital (ZSFG), San Francisco
Ages 18 to 100 · All sexes · Updated Jul 23, 2026 · NCT04362150

Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)

RecruitingEarly phase 1Healthy volunteers welcome
  • University of California San Francisco, San Francisco
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT07076862

A Study to Assess Anktiva in Patients With Long Covid-19.

RecruitingPhase 2
  • University of California - San Francisco, San Francisco
Ages 18 to 70 · All sexes · Updated May 11, 2026 · NCT07108036

Imaging Immune Activation in COVID-19

RecruitingPhase 2
  • University of California, San Francisco, San Francisco
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT04815096

About Long COVID

Anyone who has had COVID-19 can have long-lasting symptoms, know as long COVID. Learn about the symptoms and how to manage them, diagnosis, and prevention.

More about Long COVID on MedlinePlus

Long COVID trials in other cities

Other studies in San Francisco

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.